1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester

Base Information

• Chemical Name: 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester
• CAS No.: 75526-25-9
• Molecular Formula: C₁₄H₁₇NO₆S
• Molecular Weight: 327.358
• Mol file: 75526-25-9.mol

Synonyms:

Chemical Property of 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester

There total 3 articles about 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + α-phenylsulfonylamido-α-bromomalonic acid diethylester → 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester (75526-25-9)

Guidance literature:

DOI:10.1007/BF00506380

Reference yield: 35.0%

diethyl aziridine-2,2-dicarboxylate (75526-23-7) + benzenesulfonyl chloride (98-09-9) → 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester (75526-25-9)

Guidance literature:

With triethylamine;

DOI:10.1007/BF00506667

Reference yield:

diethyl α,β-dibromomethylmalonate (53084-38-1) → 1-phenylsulfonylaziridine-2,2-dicarboxylic acid diethylester (75526-25-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 37 percent / ammonia / ethanol / 48 h / 20 °C

2: 35 percent / triethylamine

With ammonia; triethylamine; In ethanol;

DOI:10.1007/BF00506667

upstream raw materials:

diazomethane

diethyl aziridine-2,2-dicarboxylate

benzenesulfonyl chloride

diethyl α,β-dibromomethylmalonate