Technology Process of C19H22O2Si
There total 3 articles about C19H22O2Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
C26H23N2O(1+)*F6P(1-); copper(l) chloride; sodium hydroxide;
In
tetrahydrofuran;
at -15 ℃;
for 12h;
Overall yield = 89%; Overall yield = 83.2 mg; enantioselective reaction;
Inert atmosphere;
DOI:10.1021/jo400888b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine; dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
2: copper(l) chloride; C26H23N2O(1+)*F6P(1-); sodium hydroxide / tetrahydrofuran / 12 h / -15 °C / Inert atmosphere
With
dmap; C26H23N2O(1+)*F6P(1-); triethylamine; copper(l) chloride; sodium hydroxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo400888b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: 3 h / 0 °C / Inert atmosphere
2.1: triethylamine; dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
3.1: copper(l) chloride; C26H23N2O(1+)*F6P(1-); sodium hydroxide / tetrahydrofuran / 12 h / -15 °C / Inert atmosphere
With
dmap; C26H23N2O(1+)*F6P(1-); sodium hydride; triethylamine; copper(l) chloride; sodium hydroxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo400888b