Technology Process of Methyl-<2-acetyl-3,4,5-trimethoxy-phenylacetat>
There total 7 articles about Methyl-<2-acetyl-3,4,5-trimethoxy-phenylacetat> which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
aluminum (III) chloride;
In
dichloromethane;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.bmc.2018.07.010
- Guidance literature:
-
Multi-step reaction with 5 steps
1: thionyl chloride / dichloromethane / 1.5 h / 20 °C
2: dimethyl sulfoxide / 36 h / 20 °C
3: acetic acid; sulfuric acid / water / 22 h / Reflux
4: sulfuric acid / 3 h / Reflux
5: aluminum (III) chloride / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
With
aluminum (III) chloride; thionyl chloride; sulfuric acid; acetic acid;
In
dichloromethane; water; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2018.07.010
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic acid; sulfuric acid / water / 22 h / Reflux
2: sulfuric acid / 3 h / Reflux
3: aluminum (III) chloride / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
With
aluminum (III) chloride; sulfuric acid; acetic acid;
In
dichloromethane; water;
DOI:10.1016/j.bmc.2018.07.010
