4-(bromomethyl)phenyl phosphorodichloridate

Base Information

• Chemical Name: 4-(bromomethyl)phenyl phosphorodichloridate
• CAS No.: 140468-02-6
• Molecular Formula: C₇H₆BrCl₂O₂P
• Molecular Weight: 303.907
• Mol file: 140468-02-6.mol

Synonyms:

Chemical Property of 4-(bromomethyl)phenyl phosphorodichloridate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(bromomethyl)phenyl phosphorodichloridate

There total 2 articles about 4-(bromomethyl)phenyl phosphorodichloridate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(bromomethyl)phenol (27079-92-1) → 4-(bromomethyl)phenyl phosphorodichloridate (140468-02-6)

Guidance literature:

With triethylamine; trichlorophosphate; In toluene;

DOI:10.1021/jm00087a023

Reference yield:

(4-hydroxyphenyl)methanol (623-05-2) → 4-(bromomethyl)phenyl phosphorodichloridate (140468-02-6)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃, pyridine / tetrahydrofuran / 18 h / Ambient temperature

2: 10.0 g / POCl₃, triethylamine / toluene

With pyridine; phosphorus tribromide; triethylamine; trichlorophosphate; In tetrahydrofuran; toluene;

DOI:10.1021/jm00087a023

Reference yield:

4-(bromomethyl)phenyl phosphorodichloridate (140468-02-6) → Phosphoric acid 4-bromomethyl-phenyl ester 3-hexadecyloxy-2-methoxy-propyl ester (140467-84-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / CCl₄ / 17 h / Ambient temperature

2: 0.5 M aq. sodium acetate / tetrahydrofuran / 2 h

With sodium acetate; triethylamine; In tetrahydrofuran; tetrachloromethane;

DOI:10.1021/jm00087a023

upstream raw materials:

4-(bromomethyl)phenol

(4-hydroxyphenyl)methanol

Downstream raw materials:

Phosphoric acid 4-bromomethyl-phenyl ester 3-hexadecyloxy-2-methoxy-propyl ester

Phosphoric acid 4-bromomethyl-phenyl ester 2-methoxy-3-(3-tetradecyl-phenoxy)-propyl ester