N-Fmoc-L-threonine Allyl Ester

Base Information

Chemical Name:N-Fmoc-L-threonine Allyl Ester
CAS No.:136523-92-7
Molecular Formula:C22H23NO5
Molecular Weight:381.428
Hs Code.:
DSSTox Substance ID:DTXSID00467098
Nikkaji Number:J875.625B
Wikidata:Q82293898
Mol file:136523-92-7.mol

Synonyms:N-Fmoc-L-threonine Allyl Ester;136523-92-7;L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2-propen-1-yl ester;prop-2-enyl (2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoate;(2S,3R)-Allyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoate;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-threonine 2-Propen-1-yl Ester;Allyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-threoninate;N-(9-Fluorenylmethoxycarbonyl)threonine Allyl Ester;DTXSID00467098;MFCD23160326;AKOS025294410;AS-80245;CS-0361179;E76381;J-006857;(2S,3R)-Allyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoate

Suppliers and Price of N-Fmoc-L-threonine Allyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Fmoc-L-threonineAllylEster
10mg
$ 125.00

Chemenu
N-Fmoc-L-threonineAllylEster 95%
10g
$ 697.00

Chemenu
N-Fmoc-L-threonineAllylEster 95%
5g
$ 378.00

Ambeed
(2S,3R)-Allyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoate 95+%
1g
$ 113.00

Ambeed
(2S,3R)-Allyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoate 95+%
250mg
$ 50.00

Ambeed
(2S,3R)-Allyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoate 95+%
100mg
$ 34.00

Total 4 raw suppliers

Chemical Property of N-Fmoc-L-threonine Allyl Ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:597.238oC at 760 mmHg
Flash Point:314.999oC
PSA：88.35000
LogP:3.20810
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:381.15762283
Heavy Atom Count:28
Complexity:543

Purity/Quality:

99% ^*data from raw suppliers

N-Fmoc-L-threonineAllylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C(=O)OCC=C)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)O
Isomeric SMILES:C[C@H]([C@@H](C(=O)OCC=C)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)O
Uses Threonine derivative.

Technology Process of N-Fmoc-L-threonine Allyl Ester

There total 5 articles about N-Fmoc-L-threonine Allyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

: 73731-37-0
Fmoc-Thr-OH

: 106-95-6
allyl bromide

: 136523-92-7
N-(9-fluorenylmethoxycarbonyl)-L-threonine allyl ester

Guidance literature:: With tetrabutylammomium bromide; water; sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1071/CH10464

Reference yield: 80.0%

: 612490-86-5
C₂₆H₃₁NO₅

: 136523-92-7
N-(9-fluorenylmethoxycarbonyl)-L-threonine allyl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 2h;

Reference yield:

: 71989-35-0,138797-71-4
Fmoc-Thr(tBu)-OH

: 136523-92-7
N-(9-fluorenylmethoxycarbonyl)-L-threonine allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: chloro-trimethyl-silane

2: hydrogenchloride / 1,4-dioxane; water / 0 - 20 °C

With hydrogenchloride; chloro-trimethyl-silane; In 1,4-dioxane; water;
DOI:10.1016/j.tetlet.2011.03.113