(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Base Information

Chemical Name:(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione
CAS No.:141762-84-7
Molecular Formula:C₄₀H₅₆O₈Si
Molecular Weight:692.965
Hs Code.:

(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Synonyms:

Suppliers and Price of (2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

There total 1 articles about (2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 130575-40-5,149400-23-7
(2S,3S,3aR,5R,6aS,7aR,8S,10R,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-10-hydroxy-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-tetradecahydro-6-oxa-benzo[de]anthracen-1-one

: 141762-84-7,149400-27-1
(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Guidance literature:: With Dess-Martin periodane; In dichloromethane; for 1h; Yield given;
DOI:10.1016/S0040-4039(00)74149-9

Reference yield:

: 141762-84-7,149400-27-1
(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

: 141762-94-9,149400-47-5,149400-48-6
(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5-hydroxy-11-methoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; for 24h;
DOI:10.1016/S0040-4039(00)74149-9

Reference yield:

: 141762-84-7,149400-27-1
(2S,3S,3aR,5R,6aS,7aR,8S,11R,11aR,11bS,11cR)-11c-(tert-Butyl-diphenyl-silanyloxymethyl)-5,11-dimethoxy-2-methoxymethoxy-3,8,11a-trimethyl-dodecahydro-6-oxa-benzo[de]anthracene-1,10-dione

: 141762-93-8
Acetic acid (2S,3S,3aR,4S,6aS,7aR,11R,11aR,11bS,11cR)-11c-(tert-butyl-diphenyl-silanyloxymethyl)-2,11-dihydroxy-3,8,11a-trimethyl-1,5,10-trioxo-1,2,3,3a,4,5,6a,7,7a,10,11,11a,11b,11c-tetradecahydro-6-oxa-benzo[de]anthracen-4-yl ester

Guidance literature:: Multi-step reaction with 10 steps

1: 10percent HCl / tetrahydrofuran / 24 h

2: POCl₃, pyridine / 1 h / 80 °C

3: 1) OsO₄, 2) NaHSO₃ / 1) pyridine, 0 deg C, 1 h, 2) 2 h

4: 75 percent / Dess-Martin periodinane reagent / CH₂Cl₂ / 1.5 h

5: 82 percent / NEt₃, DMAP / CH₂Cl₂

6: 1) LiHMDS, TMSCl, 2) NBS / 1) THF, -78 deg C to rt

7: 93 percent / Li₂CO₃, LiBr / dimethylformamide / 0.75 h / 120 °C

8: 10percent HCl / tetrahydrofuran / 0.5 h

9: DMAP, pyridine / CH₂Cl₂

10: 46 percent / BBr₃ / CH₂Cl₂ / 1) -78 deg C, 1 h, 2) -43 deg C, 1.5 h

With pyridine; hydrogenchloride; dmap; N-Bromosuccinimide; osmium(VIII) oxide; chloro-trimethyl-silane; boron tribromide; lithium carbonate; Dess-Martin periodane; sodium hydrogensulfite; triethylamine; lithium bromide; lithium hexamethyldisilazane; trichlorophosphate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)74149-9