O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a

Base Information

• Chemical Name: O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a
• CAS No.: 56153-88-9
• Molecular Formula: C₁₈H₃₇N₅O₇
• Molecular Weight: 435.521
• Mol file: 56153-88-9.mol

Synonyms:

Chemical Property of O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a

There total 4 articles about O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

O-2,4-di-O-benzyl-3-deoxy-3-N-methylacetamido-β-L-arabinopyranosyl-(1->6)-1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C1a (79248-85-4) → O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C1a (56153-88-9,56272-23-2,61769-70-8,65207-16-1)

Guidance literature:

With ammonia; sodium; at -79 ℃; for 6h;

DOI:10.1039/P19810002151

Reference yield:

1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C1a (42801-36-5) → O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C1a (56153-88-9,56272-23-2,61769-70-8,65207-16-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / silver toluene-p-sulphonate / CH₂Cl₂ / 21.25 h / 25 °C

2: 7 percent / ammonia, sodium / 6 h / -79 °C

With ammonia; silver(I) 4-methylbenzenesulfonate; sodium; In dichloromethane;

DOI:10.1039/P19810002151

Reference yield:

2,4-Di-O-benzyl-3-desoxy-3-(N-methylacetamido)-β-L-arabinopyranosylchlorid (77881-71-1) → O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C1a (56153-88-9,56272-23-2,61769-70-8,65207-16-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / silver toluene-p-sulphonate / CH₂Cl₂ / 21.25 h / 25 °C

2: 7 percent / ammonia, sodium / 6 h / -79 °C

With ammonia; silver(I) 4-methylbenzenesulfonate; sodium; In dichloromethane;

DOI:10.1039/P19810002151

upstream raw materials:

O-2,4-di-O-benzyl-3-deoxy-3-N-methylacetamido-β-L-arabinopyranosyl-(1->6)-1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a

1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a

2,4-Di-O-benzyl-3-desoxy-3-(N-methylacetamido)-β-L-arabinopyranosylchlorid

1-O-Acetyl-2,4-di-O-benzyl-3-desoxy-3-(N-methylacetamido)-L-arabinopyranose