Technology Process of 2-acetamido-4-O-allyl-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosylamine
There total 9 articles about 2-acetamido-4-O-allyl-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 82 percent / barium oxide, barium hydroxide octahydrate / dimethylformamide / 2 h / Ambient temperature; 1.) N,N-dimethylformamide, RT, 2 h, 2.) chloroform, reflux, 2 h
2: 78 percent / 60 percent aq. acetic acid / 2 h / 90 - 95 °C
3: 84 percent / pyridine / 30 h / Ambient temperature
4: 89 percent / NaOH / dimethylformamide / 5 h / Ambient temperature
5: 79 percent / 60 percent aq. acetic acid / 2 h / 90 °C
6: 56 percent / KOH / benzene; dimethylformamide / 3 h / Ambient temperature
7: sodium borohydride / dimethylformamide / 6 h / Ambient temperature
With
pyridine; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; barium hydroxide octahydrate; acetic acid; barium(II) oxide;
In
N,N-dimethyl-formamide; benzene;
DOI:10.1246/bcsj.54.3570
- Guidance literature:
-
With
sodium tetrahydroborate;
In
N,N-dimethyl-formamide;
for 6h;
Ambient temperature;
DOI:10.1246/bcsj.54.3570
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 76 percent / formic acid / 0.5 h / Ambient temperature
2: 82 percent / barium oxide, barium hydroxide octahydrate / dimethylformamide / 2 h / Ambient temperature; 1.) N,N-dimethylformamide, RT, 2 h, 2.) chloroform, reflux, 2 h
3: 78 percent / 60 percent aq. acetic acid / 2 h / 90 - 95 °C
4: 84 percent / pyridine / 30 h / Ambient temperature
5: 89 percent / NaOH / dimethylformamide / 5 h / Ambient temperature
6: 79 percent / 60 percent aq. acetic acid / 2 h / 90 °C
7: 56 percent / KOH / benzene; dimethylformamide / 3 h / Ambient temperature
8: sodium borohydride / dimethylformamide / 6 h / Ambient temperature
With
pyridine; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; formic acid; barium hydroxide octahydrate; acetic acid; barium(II) oxide;
In
N,N-dimethyl-formamide; benzene;
DOI:10.1246/bcsj.54.3570
