5-Hydroxy-7,2',4',5'-tetramethoxyflavone

Base Information

Chemical Name:5-Hydroxy-7,2',4',5'-tetramethoxyflavone
CAS No.:159119-07-0
Molecular Formula:C₁₉H₁₈O₇
Molecular Weight:358.348
Hs Code.:
DSSTox Substance ID:DTXSID801159638
Nikkaji Number:J615.036E
Wikidata:Q27134545
Metabolomics Workbench ID:24031
ChEMBL ID:CHEMBL458141

Synonyms:5-hydroxy-7,2',4',5'-tetramethoxyflavone;5-OH-TOHFL

Suppliers and Price of 5-Hydroxy-7,2',4',5'-tetramethoxyflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Hydroxy-7,2',4',5'-tetramethoxyflavone

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:358.10525291
Heavy Atom Count:26
Complexity:534

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3OC)OC)OC)O

Technology Process of 5-Hydroxy-7,2',4',5'-tetramethoxyflavone

There total 3 articles about 5-Hydroxy-7,2',4',5'-tetramethoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 480-66-0,67471-34-5
2,4,6-trihydroxyacetophenone

: 159119-07-0
5-hydroxy-7,2',4',5'-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 48 percent / pyridine / 1 h / 60 °C

2: 1.) NaOH, 2.) AcOH, conc. H₂SO₄ / 1.) DMSO, 1 h, 2.) reflux, 1 h

3: K₂CO₃ / acetone / 1 h / Heating

With pyridine; sodium hydroxide; sulfuric acid; potassium carbonate; acetic acid; In acetone;

Reference yield:

: 55270-58-1
2,4,6-tris(2,4,5-trimethoxybenzoyloxy)acetophenone

: 159119-07-0
5-hydroxy-7,2',4',5'-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOH, 2.) AcOH, conc. H₂SO₄ / 1.) DMSO, 1 h, 2.) reflux, 1 h

2: K₂CO₃ / acetone / 1 h / Heating

With sodium hydroxide; sulfuric acid; potassium carbonate; acetic acid; In acetone;