N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

Base Information

Chemical Name:N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester
CAS No.:135743-40-7
Molecular Formula:C₄₈H₇₃N₄O₁₅P
Molecular Weight:977.099
Hs Code.:

N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

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Chemical Property of N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

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Technology Process of N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

There total 3 articles about N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 135774-92-4
16-diphenylphosphonohexadecanoic acid

: 104602-46-2
N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

: 135743-40-7
N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 48h; Ambient temperature;

Reference yield:

: 506-13-8
16-hydroxyhexadecanoic acid

: 135743-40-7
N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / pyridine, DMAP / 1 h / Ambient temperature

2: 38 percent / DCC, DMAP / dimethylformamide / 48 h / Ambient temperature

With pyridine; dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;

Reference yield:

: 2524-64-3
chlorophosphoric acid diphenyl ester

: 135743-40-7
N-<2-O-(2-acetamido-1,5-anhydro-2,3-dideoxy-6-O-(16-diphenylphosphonohexadecanoyl)-D-glucitol-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / pyridine, DMAP / 1 h / Ambient temperature

2: 38 percent / DCC, DMAP / dimethylformamide / 48 h / Ambient temperature

With pyridine; dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;