1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine

Base Information

• Chemical Name: 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine
• CAS No.: 943521-72-0
• Molecular Formula: C₂₉H₃₉Cl₂F₃N₄O₂S
• Molecular Weight: 635.621

Synonyms:

Chemical Property of 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine

There total 1 articles about 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-(tert-butoxycarbonylamino)-3-(2,4-dichlorophenyl)propionyl]piperazine (943521-74-2) → 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine (943521-72-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.bmc.2007.05.026

Reference yield:

1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine (943521-72-0) + N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid (84358-13-4,174286-31-8) → (CH3)3CSONHCHCH2CH(CH3)2C6H3CF3N(CH2)4NCOCHCH2C6H3Cl2NHCOC5H9NCO2C(CH3)3

Guidance literature:

With sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmc.2007.05.026

Reference yield:

1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine (943521-72-0) + N-(t-butoxycarbonyl)glycinal (89711-08-0) → (CH3)3CSONHCHCH2CH(CH3)2C6H3CF3N(CH2)4NCOCHCH2C6H3Cl2NCHCH2NHCO2C(CH3)3

Guidance literature:

With acetic acid; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1016/j.bmc.2007.05.026

upstream raw materials:

1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-(tert-butoxycarbonylamino)-3-(2,4-dichlorophenyl)propionyl]piperazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 943521-72-0 1-{2-[(1S)-1-((S)-tert-butylsulfinylamino)-3-methylbutyl]-4-trifluoromethylphenyl}-4-[(2R)-2-amino-3-(2,4-dichlorophenyl)propionyl]piperazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send