Ethyl 2-cyclobutylacetate

Base Information

Chemical Name:Ethyl 2-cyclobutylacetate
CAS No.:38353-27-4
Molecular Formula:C₈H₁₄O₂
Molecular Weight:142.198
Hs Code.:
DSSTox Substance ID:DTXSID90558888
Wikidata:Q82441353
Mol file:38353-27-4.mol

Synonyms:Ethyl 2-cyclobutylacetate;38353-27-4;Cyclobutyl-acetic acid ethyl ester;Ethyl cyclobutylacetate;MFCD09953134;ETHYL2-CYCLOBUTYLACETATE;SCHEMBL1881523;DTXSID90558888;JPXIQOLOFKDUFB-UHFFFAOYSA-N;CS-D0101;AKOS006310683;SB12962;AS-42083;SY240747;A873858

Suppliers and Price of Ethyl 2-cyclobutylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-cyclobutylacetate
10mg
$ 45.00

SynChem
Cyclobutyl-acetic acid ethyl ester 95+%
1 g
$ 197.00

Matrix Scientific
Ethyl2-cyclobutylacetate 97%
1g
$ 537.00

Matrix Scientific
Ethyl2-cyclobutylacetate 97%
500mg
$ 357.00

Crysdot
Ethyl2-cyclobutylacetate 95+%
1g
$ 275.00

Crysdot
Ethyl2-cyclobutylacetate 95+%
250mg
$ 118.00

Chemenu
ethyl2-cyclobutylacetate 95%
1g
$ 297.00

American Custom Chemicals Corporation
CYCLOBUTYL-ACETIC ACID ETHYL ESTER 95.00%
5MG
$ 496.57

AK Scientific
Ethyl2-cyclobutylacetate
5g
$ 1268.00

Acrotein
Cyclobutyl-aceticacidethylester 97%
10g
$ 1191.67

Total 9 raw suppliers

Chemical Property of Ethyl 2-cyclobutylacetate

Chemical Property:

Boiling Point:100 °C(Press: 2 Torr)
Density:0.980±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:142.099379685
Heavy Atom Count:10
Complexity:116

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl2-cyclobutylacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CCC1

Technology Process of Ethyl 2-cyclobutylacetate

There total 2 articles about Ethyl 2-cyclobutylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 124668-80-0
(E)-ethyl 6-[(methylsulfonyl)oxy]hex-2-enoate

: 38353-27-4
ethyl cyclobutylacetate

Guidance literature:: With tetrabutylammonium perchlorate; In N,N-dimethyl-formamide; electrolysis, platinum wire gauze anode, mercury pool cathode;
DOI:10.1016/S0040-4039(00)99641-2

Reference yield:

: 38353-27-4
ethyl cyclobutylacetate

Guidance literature:: durch Wolff-Umlagerung von Cyclobutyl-diazomethylketon in Aethanol;

Reference yield:

: 38353-27-4
ethyl cyclobutylacetate

: 1217864-48-6
2-cyclobutyl-7-phenylindene

Guidance literature:: Multi-step reaction with 7 steps

1.1: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; N-ethyl-N,N-diisopropylamine / tetrahydrofuran; hexane / 1.08 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: potassium hydroxide / methanol; water / 10 h / Reflux; Inert atmosphere

3.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 20 °C / Reflux; Inert atmosphere

4.1: aluminum (III) chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

5.1: palladium diacetate; sodium carbonate; triphenylphosphine / 1,2-dimethoxyethane; water / 8 h / Reflux; Inert atmosphere

6.1: lithium aluminium tetrahydride / diethyl ether / -40 - 20 °C / Inert atmosphere

7.1: toluene-4-sulfonic acid / benzene / 2 h / Inert atmosphere; Reflux

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; aluminum (III) chloride; lithium aluminium tetrahydride; n-butyllithium; thionyl chloride; palladium diacetate; sodium carbonate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; triphenylphosphine; potassium hydroxide; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; hexane; dichloromethane; water; benzene; 4.1: Friedel-Crafts reaction / 5.1: Suzuki coupling;
DOI:10.1007/s11172-008-0217-2