N-[(Benzyloxy)carbonyl]-L-serine (pentachlorophenyl) ester

Base Information

• Chemical Name: N-[(Benzyloxy)carbonyl]-L-serine (pentachlorophenyl) ester
• CAS No.: 13673-57-9
• Molecular Formula: C17H12Cl5NO5
• Molecular Weight: 487.54600
• Mol file: 13673-57-9.mol

Synonyms:benzyloxycarbonylserine pentachlorophenyl ester;Z-Ser-OPcp;Z-L-Ser-OPCP;Pentachlorophenyl ester of benzyloxycarbonyl-L-serine;(S)-2-Benzyloxycarbonylamino-3-hydroxy-propionic acid pentachlorophenyl ester;N-benzyloxycarbonyl-L-serine pentachlorophenyl ester;

Chemical Property of N-[(Benzyloxy)carbonyl]-L-serine (pentachlorophenyl) ester

Chemical Property:

• PSA: 84.86000
• LogP: 5.53720

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[(Benzyloxy)carbonyl]-L-serine (pentachlorophenyl) ester

There total 2 articles about N-[(Benzyloxy)carbonyl]-L-serine (pentachlorophenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

Pentachlorophenol (87-86-5,67471-28-7) + N-(benzyloxycarbonyl)-L-serine (1145-80-8) → N-(benzyloxycarbonyl)-L-serine pentachlorophenyl ester (13673-57-9)

Guidance literature:

With N-ethylmorpholine;; hexamethylphosphorous triamide dichloride; In dichloromethane; 1) 0 deg C, 2 h, 2) overnight, r.t.;

Reference yield:

→ benzyloxycarbonyl-serine pentachlorophenyl ester (13673-57-9,76712-59-9)

Guidance literature:

/BRN= 143055/, Pentachlorphenol, (CH3)3CNC;

Reference yield: 93.0%

L-arginine (74-79-3,157-06-2,7004-12-8,7200-25-1,25212-18-4) + 2-Benzyloxycarbonylamino-3-hydroxy-propionic acid pentachlorophenyl ester (13673-57-9,76712-59-9) → (S)-2-((S)-2-Benzyloxycarbonylamino-3-hydroxy-propionylamino)-5-guanidino-pentanoic acid; hydrate

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1007/BF00575711

upstream raw materials:

Pentachlorophenol

N-(benzyloxycarbonyl)-L-serine

Downstream raw materials:

N-(benzyloxycarbonyl)-L-seryl-L-aspartyl-L-alanine methyl ester

Z-L-Ser-L-Tyr-OMe

2-acetamido-3,4,6-tri-O-acetyl-1-N--2-deoxy-β-D-glucopyranosylamine

Z-L-Ser-L-Tyr-N₂H₃

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