(-)-1,2-BIS((2S,5S)-2,5-DIETHYLPHOSPHOLANO)ETHANE

Base Information

• Chemical Name: (-)-1,2-BIS((2S,5S)-2,5-DIETHYLPHOSPHOLANO)ETHANE
• CAS No.: 136779-27-6
• Molecular Formula: C18H36P2
• Molecular Weight: 314.42600
• Mol file: 136779-27-6.mol

Synonyms:(-)-1,2-Bis[(2S,5S)-2,5-diethyl-1-phospholanyl]ethane;(2S,5S)-1-[2-[(2S,5S)-2,5-diethylphospholan-1-yl]ethyl]-2,5-diethylphospholane;(S,S)-Et-BPE;

Chemical Property of (-)-1,2-BIS((2S,5S)-2,5-DIETHYLPHOSPHOLANO)ETHANE

Chemical Property:

• Refractive Index: n 20/D 1.5243
• Boiling Point: 104-106oC 0,5mm
• PSA: 27.18000
• LogP: 6.65220
• Sensitive.: air sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

(-)-1,2-Bis((2S,5S)-2,5-diethylphospholano)ethane, 98+% (S,S)-Et-BPE ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 36/37/38-17
• Safety Statements: 26-36/37/39-6

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

Technology Process of (-)-1,2-BIS((2S,5S)-2,5-DIETHYLPHOSPHOLANO)ETHANE

There total 2 articles about (-)-1,2-BIS((2S,5S)-2,5-DIETHYLPHOSPHOLANO)ETHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,R)-octane-3,6-diol (129619-37-0) → (S)-Et-BPE (136779-27-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) SOCl₂, 2.) RuCl₃, NaIO₄

With ruthenium trichloride; sodium periodate; thionyl chloride;

DOI:10.1021/ja00022a047

Reference yield:

1,2-diphosphinoethane (5518-62-7) + (3R,6R)-3,6-octanediol cyclic sulfate (136705-67-4,151124-02-6) → (S)-Et-BPE (136779-27-6)

Guidance literature:

Multistep reaction;

DOI:10.1021/ja00022a047

upstream raw materials:

1,2-diphosphinoethane

(3R,6R)-3,6-octanediol cyclic sulfate

(R,R)-octane-3,6-diol

Refernces