Technology Process of 3-<3α-(2-acetoxyethyl)-2,2,4α-trimethylcyclohexan-1α-yl>propionic acid
There total 15 articles about 3-<3α-(2-acetoxyethyl)-2,2,4α-trimethylcyclohexan-1α-yl>propionic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
jones reagent;
In
acetone;
for 0.5h;
Yield given;
Ambient temperature;
DOI:10.1248/cpb.36.4711
- Guidance literature:
-
Multi-step reaction with 11 steps
1: 70.5 percent / toluene / 24 h / 100 °C
2: 97.3 percent / PtO2, hydrogen / ethyl acetate / 2 h / Ambient temperature
3: 100 percent / Et3N / CH2Cl2 / 0.33 h / 0 °C
4: dimethylsulfoxide / 7 h / 100 - 105 °C
5: 240 mg / LiBH4 / diethyl ether / 3 h / Heating
6: pyridinium p-toluenesulfonate / CH2Cl2 / 13 h / Ambient temperature
7: 185 mg / diisobutylaluminum hydride / hexane; toluene / 1 h / Ambient temperature
8: 176 mg / 1.) LiAlH4; 2.) NaOH, water / diethyl ether / 0.5 h / -15 °C
9: 179 mg / pyridine / 1 h / Ambient temperature
10: p-TsOH / ethanol / 3 h / Ambient temperature
11: Jones reagent / acetone / 0.5 h / Ambient temperature
With
platinum(IV) oxide; sodium hydroxide; lithium aluminium tetrahydride; lithium borohydride; jones reagent; water; hydrogen; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; toluene-4-sulfonic acid; triethylamine;
In
pyridine; diethyl ether; ethanol; hexane; dichloromethane; dimethyl sulfoxide; ethyl acetate; acetone; toluene;
DOI:10.1248/cpb.36.4711
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridinium p-toluenesulfonate / CH2Cl2 / 13 h / Ambient temperature
2: 185 mg / diisobutylaluminum hydride / hexane; toluene / 1 h / Ambient temperature
3: 176 mg / 1.) LiAlH4; 2.) NaOH, water / diethyl ether / 0.5 h / -15 °C
4: 179 mg / pyridine / 1 h / Ambient temperature
5: p-TsOH / ethanol / 3 h / Ambient temperature
6: Jones reagent / acetone / 0.5 h / Ambient temperature
With
sodium hydroxide; lithium aluminium tetrahydride; jones reagent; water; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; toluene-4-sulfonic acid;
In
pyridine; diethyl ether; ethanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1248/cpb.36.4711
![Acetic acid 2-[(1R,3R,6R)-3-(3-hydroxy-propyl)-2,2,6-trimethyl-cyclohexyl]-ethyl ester](/Databaselist/images/loading.webp)
