Technology Process of (R)-tris(4-bromophenyl)((1,2,3,4-tetrahydronaphthalen-1-yl)-oxy)silane
There total 11 articles about (R)-tris(4-bromophenyl)((1,2,3,4-tetrahydronaphthalen-1-yl)-oxy)silane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Levamisole; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / -78 °C / Inert atmosphere; Molecular sieve; Resolution of racemate
1.2: 24 h / -78 °C / Inert atmosphere; Molecular sieve; Resolution of racemate
2.1: Levamisole; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / -78 °C / Inert atmosphere; Schlenk technique; Molecular sieve
2.2: -78 °C / Inert atmosphere; Schlenk technique; Molecular sieve
With
Levamisole; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
DOI:10.1021/jo402569h
- Guidance literature:
-
(R)-1-tetralol;
With
Levamisole; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
at -78 ℃;
Inert atmosphere;
Schlenk technique;
Molecular sieve;
tris(4-bromophenyl)chlorosilane;
In
tetrahydrofuran;
at -78 ℃;
Inert atmosphere;
Schlenk technique;
Molecular sieve;
DOI:10.1021/jo402569h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / pentane / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: sulfuryl dichloride / tetrachloromethane / Inert atmosphere; Reflux
3.1: Levamisole; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / -78 °C / Inert atmosphere; Schlenk technique; Molecular sieve
3.2: -78 °C / Inert atmosphere; Schlenk technique; Molecular sieve
With
n-butyllithium; sulfuryl dichloride; Levamisole; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; tetrachloromethane; pentane;
DOI:10.1021/jo402569h
