Technology Process of methyl 2,6,3',6'-tetra-O-benzyl-4'-O-imidazolylsulphonyl-3,2'-O-isopropylidene-β-lactoside
There total 4 articles about methyl 2,6,3',6'-tetra-O-benzyl-4'-O-imidazolylsulphonyl-3,2'-O-isopropylidene-β-lactoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) tributyltin oxide, molecular sieves 3A; 2.) N-methylimidazole / 1.) toluene, 120 deg C, 20 h; 2.) 100 deg C, 55 h
2: 65 percent / pyridinium toluene-p-sulphonate / dimethylformamide / 40 h / 0 - 4 °C
3: 1.) sodium hydride / 1.) DMF, r.t., 15 min; 2.) 60-70 deg C, 1 h; 3.) DMF, -30 deg C, 7 h
With
1-methyl-1H-imidazole; 3 A molecular sieve; tributyltin oxide; pyridinium p-toluenesulfonate; sodium hydride;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 65 percent / pyridinium toluene-p-sulphonate / dimethylformamide / 40 h / 0 - 4 °C
2: 1.) sodium hydride / 1.) DMF, r.t., 15 min; 2.) 60-70 deg C, 1 h; 3.) DMF, -30 deg C, 7 h
With
pyridinium p-toluenesulfonate; sodium hydride;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) tributyltin oxide, molecular sieves 3A; 2.) N-methylimidazole / 1.) toluene, 120 deg C, 20 h; 2.) 100 deg C, 55 h
2: 65 percent / pyridinium toluene-p-sulphonate / dimethylformamide / 40 h / 0 - 4 °C
3: 1.) sodium hydride / 1.) DMF, r.t., 15 min; 2.) 60-70 deg C, 1 h; 3.) DMF, -30 deg C, 7 h
With
1-methyl-1H-imidazole; 3 A molecular sieve; tributyltin oxide; pyridinium p-toluenesulfonate; sodium hydride;
In
N,N-dimethyl-formamide;
