3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine

Base Information

• Chemical Name: 3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine
• CAS No.: 96405-79-7
• Molecular Formula: C₃₁H₂₉NO₃
• Molecular Weight: 463.576
• Mol file: 96405-79-7.mol

Synonyms:

Chemical Property of 3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine

There total 1 articles about 3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(3-Benzyloxy-benzyl)-(3-benzyloxy-4-methoxy-benzyl)-(2,2-dimethoxy-ethyl)-amine → 3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine (96405-79-7)

Guidance literature:

With hydrogenchloride; In acetone;

DOI:10.1039/c39840001646

Reference yield: 89.0%

3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine (96405-79-7) → (S)-3,9-Bis-benzyloxy-2-methoxy-7,12-dihydro-5H-6,12-methano-dibenzo[c,f]azocine (96444-11-0)

Guidance literature:

With O,O'-dibenzoyl-L-tartaric acid;

DOI:10.1039/c39840001646

Reference yield:

3,9-dibenzyloxy-2-methoxytetrahydro-6,12-methanodibenzazocine (96405-79-7) → (S)-7-Benzyloxy-4-(4-benzyloxy-2-formyl-5-methoxy-phenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / O,O'-dibenzoyl-L-(+)-tartaric acid

2: m-chloroperbenzoic acid

3: 8 percent / tBu-OK / 2-methyl-propan-2-ol

With potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; O,O'-dibenzoyl-L-tartaric acid; In tert-butyl alcohol;

DOI:10.1039/c39840001646

Downstream raw materials:

(S)-3,9-Bis-benzyloxy-2-methoxy-7,12-dihydro-5H-6,12-methano-dibenzo[c,f]azocine

(4S)-4-(4-hydroxyphenyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol

(S)-3,9-Bis-benzyloxy-2-methoxy-7,12-dihydro-5H-6,12-methano-dibenzo[c,f]azocine 6-oxide

(S)-7-(benzyloxy)-4-(4-(benzyloxy)phenyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline