Technology Process of 4-[Hydroxy-(5,5,8,8-tetramethyl-4-oxo-3,4,5,6,7,8-hexahydro-2H-1-thia-anthracen-3-yl)-methyl]-benzoic acid methyl ester
There total 7 articles about 4-[Hydroxy-(5,5,8,8-tetramethyl-4-oxo-3,4,5,6,7,8-hexahydro-2H-1-thia-anthracen-3-yl)-methyl]-benzoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: chlorosulfonic acid / 3 h / Ambient temperature
2: Zn, concd HCl / ethanol / 1 h / Heating
3: 24 g / NaOMe / methanol / 1 h / Ambient temperature
4: 44 percent / 5 N NaOH / methanol / 2 h / Ambient temperature
5: thionyl chloride / benzene / 0.67 h / Heating
6: AlCl3 / CS2 / 4 h / Heating
7: NaOH / methanol / 24 h / Ambient temperature
With
hydrogenchloride; chlorosulfonic acid; sodium hydroxide; aluminium trichloride; thionyl chloride; sodium methylate; zinc;
In
methanol; carbon disulfide; ethanol; benzene;
DOI:10.1021/jm00016a020
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 24 g / NaOMe / methanol / 1 h / Ambient temperature
2: 44 percent / 5 N NaOH / methanol / 2 h / Ambient temperature
3: thionyl chloride / benzene / 0.67 h / Heating
4: AlCl3 / CS2 / 4 h / Heating
5: NaOH / methanol / 24 h / Ambient temperature
With
sodium hydroxide; aluminium trichloride; thionyl chloride; sodium methylate;
In
methanol; carbon disulfide; benzene;
DOI:10.1021/jm00016a020
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Zn, concd HCl / ethanol / 1 h / Heating
2: 24 g / NaOMe / methanol / 1 h / Ambient temperature
3: 44 percent / 5 N NaOH / methanol / 2 h / Ambient temperature
4: thionyl chloride / benzene / 0.67 h / Heating
5: AlCl3 / CS2 / 4 h / Heating
6: NaOH / methanol / 24 h / Ambient temperature
With
hydrogenchloride; sodium hydroxide; aluminium trichloride; thionyl chloride; sodium methylate; zinc;
In
methanol; carbon disulfide; ethanol; benzene;
DOI:10.1021/jm00016a020
