3-Amino-5-(phenylamino)-4-isothiazolecarboxamide

Base Information

Chemical Name:3-Amino-5-(phenylamino)-4-isothiazolecarboxamide
CAS No.:117376-88-2
Molecular Formula:C₁₀H₁₀N₄OS
Molecular Weight:234.282
Hs Code.:
DSSTox Substance ID:DTXSID601239446

Synonyms:3-Amino-5-(phenylamino)-4-isothiazolecarboxamide;117376-88-2;DTXSID601239446

Suppliers and Price of 3-Amino-5-(phenylamino)-4-isothiazolecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Amino-5-(phenylamino)-4-isothiazolecarboxamide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:234.05753213
Heavy Atom Count:16
Complexity:257

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=C(C(=NS2)N)C(=O)N

Technology Process of 3-Amino-5-(phenylamino)-4-isothiazolecarboxamide

There total 3 articles about 3-Amino-5-(phenylamino)-4-isothiazolecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 117377-43-2
3-amino-5-(phenylamino)isothiazole-4-carbonitrile

: 117376-88-2
3-amino-5-(phenylamino)isothiazole-4-carboxamide

Guidance literature:: With sodium hydroxide; for 8h; Heating;

Reference yield:

: 17823-65-3
2-cyano-3-methylthio-3-phenylaminoacrylonitrile

: 117376-88-2
3-amino-5-(phenylamino)isothiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / 1.) Na₂S, 2.) aq. chloramine / dimethylformamide; H₂O / Ambient temperature; 1.) 24 h, 2.) 24 h

2: 77 percent / 10percent NaOH / 8 h / Heating

With sodium sulfide; sodium hydroxide; chloroamine; In water; N,N-dimethyl-formamide;

Reference yield:

: 103-72-0
phenyl isothiocyanate

: 117376-88-2
3-amino-5-(phenylamino)isothiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / 1.) sodium ethoxide, 2.) aq. chloramine / ethanol / Ambient temperature; 1.) 12 h, 2.) 24 h

2: 77 percent / 10percent NaOH / 8 h / Heating

With sodium hydroxide; chloroamine; sodium ethanolate; In ethanol;