[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Base Information

Chemical Name:[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt
CAS No.:1079989-99-3
Molecular Formula:C₈H₁₉NO₅*C₂₀H₁₅ClFN₅O₅S₂
Molecular Weight:733.196
Hs Code.:

[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Synonyms:

Suppliers and Price of [4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

There total 9 articles about [4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 936500-94-6
Elinogrel

: 14216-22-9
N-ethyl-D-glucamine

: 1079989-99-3
[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Guidance literature:: In water; for 2h;

Reference yield:

: 207346-42-7
2-amino-4,5-difluoro-benzoic acid,methyl ester

: 1079989-99-3
[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Guidance literature:: Multi-step reaction with 7 steps

1.1: dichloromethane / 3 h / 40 °C

2.1: triethylamine / tetrahydrofuran / 0.42 h

2.2: 2 h / 65 °C

3.1: methanol; sodium methylate / tetrahydrofuran / 4.33 h / 25 - 30 °C

4.1: hydrogenchloride / 1,4-dioxane / 5 - 6 h / 20 - 30 °C

5.1: ethanol; dimethyl sulfoxide / 5.67 h / 25 - 110 °C

6.1: dimethyl sulfoxide / 15 h / 65 °C

7.1: water / 2 h

With hydrogenchloride; methanol; sodium methylate; triethylamine; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water; dimethyl sulfoxide;

Reference yield:

: C₉H₅F₂NO₃

: 1079989-99-3
[4-(6-chloro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea N-ethylglucamine salt

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / N,N-dimethyl-formamide / 20 °C

2: methanol; sodium methylate / tetrahydrofuran / 4.33 h / 25 - 30 °C

3: hydrogenchloride / 1,4-dioxane / 5 - 6 h / 20 - 30 °C

4: ethanol; dimethyl sulfoxide / 5.67 h / 25 - 110 °C

5: dimethyl sulfoxide / 15 h / 65 °C

6: water / 2 h

With hydrogenchloride; methanol; sodium methylate; triethylamine; In tetrahydrofuran; 1,4-dioxane; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;