4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

Base Information

Chemical Name:4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid
CAS No.:1315344-81-0
Molecular Formula:C₁₄H₁₉FN₂O₃
Molecular Weight:281.316
Hs Code.:

4-<sup>(18)</sup>F-fluorosuberoylanilide hydroxamic acid

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Chemical Property of 4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

Chemical Property:

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Technology Process of 4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

There total 4 articles about 4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1315344-79-6
C₁₅H₂₀⁽¹⁸⁾FNO₃

: 1315344-81-0
4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

Guidance literature:: With hydroxylamine; sodium hydroxide; In methanol; water; at 20 ℃; for 0.05h;
DOI:10.1021/jm200620f

Reference yield:

: 93639-14-6
4-<18F>fluoroaniline

: 1315344-81-0
4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.08 h / 20 °C

2: hydroxylamine; sodium hydroxide / methanol; water / 0.05 h / 20 °C

With hydroxylamine; sodium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/jm200620f

Reference yield:

: 16447-86-2
4-<18F>-fluoronitrobenzene

: 1315344-81-0
4-⁽¹⁸⁾F-fluorosuberoylanilide hydroxamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate; palladium 10% on activated carbon / 20 °C

2: tetrahydrofuran / 0.08 h / 20 °C

3: hydroxylamine; sodium hydroxide / methanol; water / 0.05 h / 20 °C

With sodium tetrahydroborate; palladium 10% on activated carbon; hydroxylamine; sodium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/jm200620f