16447-86-2Relevant articles and documents
“In-loop” 18F-fluorination: A proof-of-concept study
Dahl, Kenneth,Garcia, Armando,Stephenson, Nickeisha A.,Vasdev, Neil
, p. 292 - 297 (2019)
There is a great demand to develop more cost-efficient and robust manufacturing processes for fluorine-18 (18F) labelled compounds and radiopharmaceuticals. Herein, we present to our knowledge the first radiofluorination “in-loop,” where [
A general protocol for Cu-mediated fluoro-deamination: Sandmeyer fluorination of diverse aromatic substrates
Pérez-García, R. Manuel,Gr?nnevik, Gaute,Riss, Patrick J.
supporting information, p. 1011 - 1015 (2021/02/16)
A Cu(I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised. The method affords fluorinated aromatic products directly from anilines under both no-carrier added and stoichiometric conditions. Isolated radiochemical yields ran
[18F]Ethenesulfonyl Fluoride as a Practical Radiofluoride Relay Reagent
Zhang, Bo,Fraser, Benjamin H.,Klenner, Mitchell A.,Chen, Zhen,Liang, Steven H.,Massi, Massimiliano,Robinson, Andrea J.,Pascali, Giancarlo
supporting information, p. 7613 - 7617 (2019/05/17)
Fluorine-18 is the most utilized radioisotope in positron emission tomography (PET), but the wide application of fluorine-18 radiopharmaceuticals is hindered by its challenging labelling conditions. As such, many potentially important radiotracers remain
