(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Base Information

• Chemical Name: (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
• CAS No.: 475473-26-8
• Molecular Formula: C₅H₄ClNO₅Ru
• Molecular Weight: 294.613
• Mol file: 475473-26-8.mol

Synonyms:

Chemical Property of (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Chemical Property:

• Storage Temp.: ?20°C
• Solubility.: H2O: soluble20mg/mL, clear

Purity/Quality:

98%,99%, ^*data from raw suppliers

CORM 3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H2O2-induced apoptosis using primary rabbit lens epithelial cells.

Technology Process of (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

There total 1 articles about (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

dichlorotricarbonylruthenium(II) dimer + glycine (56-40-6,18875-39-3,25718-94-9) → tricarbonylchloro(glycinato)ruthenium(II) (475473-26-8)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.ejmech.2013.12.041

upstream raw materials:

glycine

Refernces

• 1、 Wang, Pengpeng,Liu, Huapeng,Zhao, Quanyi,Chen, Yonglin,Liu, Bin,Zhang, Baoping,Zheng, Qian. "Syntheses and evaluation of drug-like properties of CO-releasing molecules containing ruthenium and group 6 metal". . p. 199 - 215. Retrieved 2014/02/14.