2-phenylnaphtho[2,3-d]oxaphosphole

Base Information

• Chemical Name: 2-phenylnaphtho[2,3-d]oxaphosphole
• CAS No.: 1402752-10-6
• Molecular Formula: C₁₇H₁₁OP
• Molecular Weight: 262.248
• Mol file: 1402752-10-6.mol

Synonyms:

Chemical Property of 2-phenylnaphtho[2,3-d]oxaphosphole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenylnaphtho[2,3-d]oxaphosphole

There total 4 articles about 2-phenylnaphtho[2,3-d]oxaphosphole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.8%

3-phosphino-2-naphthol (1402752-07-1) + N-phenyl-benzimidoyl chloride (4903-36-0) → 2-phenylnaphtho[2,3-d]oxaphosphole (1402752-10-6)

Guidance literature:

In tetrahydrofuran; for 20h; Inert atmosphere; Reflux; Schlenk technique;

DOI:10.1039/c2dt30902e

Reference yield:

β-naphthol (135-19-3) → 2-phenylnaphtho[2,3-d]oxaphosphole (1402752-10-6)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 12 h / Inert atmosphere; Schlenk technique

2: lithium diisopropyl amide / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere; Schlenk technique

3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Inert atmosphere; Reflux; Schlenk technique

4: tetrahydrofuran / 20 h / Inert atmosphere; Reflux; Schlenk technique

With lithium aluminium tetrahydride; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; 2: |Fries Phenol Ester Rearrangement;

DOI:10.1039/c2dt30902e

Reference yield:

diethyl (3-hydroxy-2-naphthyl)phosphonate (131180-33-1) → 2-phenylnaphtho[2,3-d]oxaphosphole (1402752-10-6)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Inert atmosphere; Reflux; Schlenk technique

2: tetrahydrofuran / 20 h / Inert atmosphere; Reflux; Schlenk technique

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1039/c2dt30902e

upstream raw materials:

3-phosphino-2-naphthol

N-phenyl-benzimidoyl chloride

β-naphthol

diethyl naphthalen-2-yl phosphate