3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid

Base Information

Chemical Name:3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid
CAS No.:187870-25-3
Molecular Formula:C₁₄H₁₄ClNO₂
Molecular Weight:263.724
Hs Code.:
European Community (EC) Number:894-862-2
Mol file:187870-25-3.mol

Synonyms:3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid;187870-25-3;3-(4-chlorophenyl)-4-pyrrol-1-ylbutanoic acid;MFCD05260925;AKOS023390556;LS-09787;EN300-302353;3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoicacid

Suppliers and Price of 3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid
5g
$ 700.00

Matrix Scientific
3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid
1g
$ 200.00

Matrix Scientific
3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid
0.500g
$ 160.00

Total 2 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:263.0713064
Heavy Atom Count:18
Complexity:271

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN(C=C1)CC(CC(=O)O)C2=CC=C(C=C2)Cl

Technology Process of 3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid

There total 1 articles about 3-(4-Chlorophenyl)-4-(1H-pyrrol-1-yl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 696-59-3
cis,trans-2,5-dimethoxytetrahydrofuran

: 1134-47-0
4-amino-3-(4-chlorophenyl)butanoic acid

: 187870-25-3
3-(4-chlorophenyl)-4-pyrrol-1-ylbutyric acid

Guidance literature:: With acetic acid; for 1h; Heating;
DOI:10.1002/jhet.5570330623

Reference yield:

: 187870-25-3
3-(4-chlorophenyl)-4-pyrrol-1-ylbutyric acid

: 8-amino-6-(4-chlorophenyl)-5,6,7,8-tetrahydroindolizine

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) Et₃N / 1.) acetone, 0 deg C, 30 min, 2.) acetone, 0 deg C, 30 min

2: acetone / 1 h / Heating

3: 90 percent / 1.) POCl₃, 2.) NaHCO₃, HClO₄ / toluene / 2 h / Heating

4: NH₃ / methanol / 0.17 h

5: NaBH₄ / methanol / 1 h / Ambient temperature

With sodium tetrahydroborate; perchloric acid; ammonia; sodium hydrogencarbonate; triethylamine; trichlorophosphate; In methanol; acetone; toluene;
DOI:10.1002/jhet.5570330623

Reference yield:

: 187870-25-3
3-(4-chlorophenyl)-4-pyrrol-1-ylbutyric acid

: Benzyl-[(6R,8R)-6-(4-chloro-phenyl)-5,6,7,8-tetrahydro-indolizin-8-yl]-amine

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) Et₃N / 1.) acetone, 0 deg C, 30 min, 2.) acetone, 0 deg C, 30 min

2: acetone / 1 h / Heating

3: 90 percent / 1.) POCl₃, 2.) NaHCO₃, HClO₄ / toluene / 2 h / Heating

4: 56 percent / K₂₃CO₃ / dimethylformamide / 2 h / Heating

5: 57 percent / NaBH₄ / methanol / 1 h / Ambient temperature

With sodium tetrahydroborate; perchloric acid; sodium hydrogencarbonate; potassium carbonate; triethylamine; trichlorophosphate; In methanol; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/jhet.5570330623