C₁₁H₁₄FN

Base Information

• Chemical Name: C₁₁H₁₄FN
• CAS No.: 1451270-98-6
• Molecular Formula: C₁₁H₁₄FN
• Molecular Weight: 179.237
• Mol file: 1451270-98-6.mol

Synonyms:

Chemical Property of C₁₁H₁₄FN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₄FN

There total 3 articles about C₁₁H₁₄FN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluoro-2-(3-methylbut-2-en-1-yl)-1-nitrobenzene (1451270-97-5) → C11H14FN (1451270-98-6)

Guidance literature:

With ammonium formate; zinc; In tetrahydrofuran; methanol; for 1h;

DOI:10.1002/ejoc.201201363

Reference yield:

4-fluoro-2-iodo-1-nitrobenzene (41860-64-4) → C11H14FN (1451270-98-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phenylmagnesium bromide; copper(l) cyanide; lithium chloride / tetrahydrofuran / 0.33 h / -40 °C / Inert atmosphere

1.2: 255 / 2 h / Inert atmosphere

2.1: zinc; ammonium formate / tetrahydrofuran; methanol / 1 h

With copper(l) cyanide; ammonium formate; phenylmagnesium bromide; lithium chloride; zinc; In tetrahydrofuran; methanol;

DOI:10.1002/ejoc.201201363

Reference yield:

prenyl bromide (870-63-3) → C11H14FN (1451270-98-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phenylmagnesium bromide; copper(l) cyanide; lithium chloride / tetrahydrofuran / 0.33 h / -40 °C / Inert atmosphere

1.2: 255 / 2 h / Inert atmosphere

2.1: zinc; ammonium formate / tetrahydrofuran; methanol / 1 h

With copper(l) cyanide; ammonium formate; phenylmagnesium bromide; lithium chloride; zinc; In tetrahydrofuran; methanol;

DOI:10.1002/ejoc.201201363

upstream raw materials:

prenyl bromide

4-fluoro-2-(3-methylbut-2-en-1-yl)-1-nitrobenzene

4-fluoro-2-iodo-1-nitrobenzene