Mycophenolic Acid Cyclopropane Analogue

Base Information

Chemical Name:Mycophenolic Acid Cyclopropane Analogue
CAS No.:125198-40-5
Molecular Formula:C₁₈H₂₂O₆
Molecular Weight:334.369
Hs Code.:
Mol file:125198-40-5.mol

Synonyms:

Suppliers and Price of Mycophenolic Acid Cyclopropane Analogue

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-CyclopropaneMycophenolicAcid
10mg
$ 150.00

Total 7 raw suppliers

Chemical Property of Mycophenolic Acid Cyclopropane Analogue

Chemical Property:

Melting Point:130-135 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling Point:611.8±55.0 °C(Predicted)
PKA:4.78±0.10(Predicted)
Density:1.316±0.06 g/cm3(Predicted)
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

> 95% ^*data from raw suppliers

1-CyclopropaneMycophenolicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Cyclopropane Mycophenolic Acid is a non-active analogue of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.

Technology Process of Mycophenolic Acid Cyclopropane Analogue

There total 1 articles about Mycophenolic Acid Cyclopropane Analogue which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-11-6
diiodomethane

: 24280-93-1
mycophenolic acid

: 125198-40-5
3-[2-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-isobenzofuran-5-ylmethyl)-1-methyl-cyclopropyl]-propionic acid

Guidance literature:: With copper(l) chloride; zinc; Yield given. Multistep reaction; 1.) THF, reflux, 15 min, 2.) reflux, 2 h;
DOI:10.1021/jm00164a057