Technology Process of ANPB-DDAO
There total 4 articles about ANPB-DDAO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
at 20 ℃;
for 6h;
Inert atmosphere;
DOI:10.1002/anie.201106559
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium tert-butylate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
2: sodium hydride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere
3: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C
4: tetrabutylammomium bromide; palladium diacetate; potassium carbonate / ethanol; water / 0.17 h / 150 °C / Microwave irradiation
5: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
With
di-isopropyl azodicarboxylate; potassium tert-butylate; tetrabutylammomium bromide; palladium diacetate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
4: Suzuki coupling;
DOI:10.1002/anie.201106559
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere
2: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C
3: tetrabutylammomium bromide; palladium diacetate; potassium carbonate / ethanol; water / 0.17 h / 150 °C / Microwave irradiation
4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
With
di-isopropyl azodicarboxylate; tetrabutylammomium bromide; palladium diacetate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; ethanol; water;
3: Suzuki coupling;
DOI:10.1002/anie.201106559
