SnAP-TM Reagent

Base Information

Chemical Name:SnAP-TM Reagent
CAS No.:1452829-00-3
Molecular Formula:C₁₅H₃₅NSSn
Molecular Weight:380.226
Hs Code.:
Mol file:1452829-00-3.mol

Synonyms:

Suppliers and Price of SnAP-TM Reagent

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
SnAP TM Reagent
1g
$ 135.00

Atlantic Research Chemicals
2-(Tributylstannylmethylsulfanyl)ethanamine 95%
1gm:
$ 420.61

Total 3 raw suppliers

Chemical Property of SnAP-TM Reagent

Chemical Property:

Refractive Index:n/D1.512
Boiling Point:383.3±52.0 °C(Predicted)
PKA:9.08±0.10(Predicted)
Flash Point:>230℃
Density:1.158 at 25℃
Storage Temp.:-20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

SnAP TM Reagent ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated?N-heterocycles. The synthesis of?N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl,?glyoxyl,?aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the?Bode Research Group

Technology Process of SnAP-TM Reagent

There total 3 articles about SnAP-TM Reagent which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 66222-29-5
tri-n-butylstannylmethyl iodide

: 60-23-1
Cysteamine

: 1452829-00-3
(2-(((tributylstannyl)methyl)thio)ethanamine)

Guidance literature:: With potassium carbonate; In ethanol; water; at 70 ℃; for 12h; Inert atmosphere;
DOI:10.1002/anie.201208064

Reference yield:

: 27490-33-1
tri-n-butylstannylmethanol

: 1452829-00-3
(2-(((tributylstannyl)methyl)thio)ethanamine)

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere

2: potassium carbonate / ethanol; water / 12 h / 70 °C / Inert atmosphere

With N-iodo-succinimide; potassium carbonate; triphenylphosphine; In tetrahydrofuran; ethanol; water;
DOI:10.1002/anie.201208064

Reference yield:

: 688-73-3
tri-n-butyl-tin hydride

: 1452829-00-3
(2-(((tributylstannyl)methyl)thio)ethanamine)

Guidance literature:: Multi-step reaction with 3 steps

1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere

1.2: 4 h / 0 - 20 °C / Inert atmosphere

2.1: N-iodo-succinimide; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere

3.1: potassium carbonate / ethanol; water / 12 h / 70 °C / Inert atmosphere

With N-iodo-succinimide; n-butyllithium; potassium carbonate; diisopropylamine; triphenylphosphine; In tetrahydrofuran; ethanol; hexane; water;
DOI:10.1002/anie.201208064