(2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide

Base Information

• Chemical Name: (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide
• CAS No.: 1480371-38-7
• Molecular Formula: C₃₄H₂₃N₂OP
• Molecular Weight: 506.543
• Mol file: 1480371-38-7.mol

Synonyms:

Chemical Property of (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide

There total 5 articles about (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

3-bromophenanthroline (66127-01-3) + diphenyl(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)phosphineoxide → (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide (1480371-38-7)

Guidance literature:

With palladium diacetate; potassium carbonate; tricyclohexylphosphine; In ethanol; water; toluene; at 90 ℃; Inert atmosphere;

DOI:10.1002/adfm.201401685

Reference yield:

2-bromo-6-diphenylphosphinonaphthalene → (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide (1480371-38-7)

Guidance literature:

Multi-step reaction with 3 steps

1: dihydrogen peroxide / dichloromethane / 20 °C

2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water / 2 h / 80 °C / Inert atmosphere

3: palladium diacetate; tricyclohexylphosphine; potassium carbonate / water; toluene; ethanol / 90 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; dihydrogen peroxide; potassium acetate; palladium diacetate; potassium carbonate; tricyclohexylphosphine; In ethanol; dichloromethane; water; toluene; 3: |Suzuki Coupling;

DOI:10.1002/adfm.201401685

Reference yield:

2,6-dibromonaphthalene (13720-06-4) → (2-(1,10-phenanthrolin-3-yl)naphth-6-yl)diphenylphosphine oxide (1480371-38-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: dihydrogen peroxide / dichloromethane / 20 °C

3.1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water / 2 h / 80 °C / Inert atmosphere

4.1: palladium diacetate; tricyclohexylphosphine; potassium carbonate / water; toluene; ethanol / 90 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; n-butyllithium; dihydrogen peroxide; potassium acetate; palladium diacetate; potassium carbonate; tricyclohexylphosphine; In tetrahydrofuran; ethanol; hexane; dichloromethane; water; toluene; 4.1: |Suzuki Coupling;

DOI:10.1002/adfm.201401685

upstream raw materials:

3-bromophenanthroline

2,6-dibromonaphthalene

chloro-diphenylphosphine