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66127-01-3

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66127-01-3 Usage

General Description

3-Bromo-1,10-phenanthroline is a chemical compound consisting of a phenanthroline ring with a bromine atom attached at the 3-position. It is commonly used in laboratory settings as a chelating agent for transition metal ions, particularly in spectrophotometric and fluorometric analyses. The presence of the bromine atom can affect its reactivity and solubility, making it useful for specific applications. 3-BROMO-1,10-PHENANTHROLINE has been studied for its potential as a fluorescent probe for detecting and quantifying metal ions in biological and environmental samples. Additionally, it has also been investigated for its role in the synthesis of coordination complexes and in catalytic reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 66127-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,1,2 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 66127-01:
(7*6)+(6*6)+(5*1)+(4*2)+(3*7)+(2*0)+(1*1)=113
113 % 10 = 3
So 66127-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H7BrN2/c13-10-6-9-4-3-8-2-1-5-14-11(8)12(9)15-7-10/h1-7H

66127-01-3 Well-known Company Product Price

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  • TCI America

  • (B2632)  3-Bromo-1,10-phenanthroline  >98.0%(HPLC)(T)

  • 66127-01-3

  • 200mg

  • 1,750.00CNY

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66127-01-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Bromo-1,10-phenanthroline

1.2 Other means of identification

Product number -
Other names 3-BROMO-1,10-PHENANTHROLINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66127-01-3 SDS

66127-01-3Relevant articles and documents

Photobiological activity of Ru(ll) dyads based on (Pyren-1 -yl)ethynyl derivatives of 1, 10-Phenanthroline

Monro, Susan,Scott, John,Chouai, Abdellatif,Lincoln, Richard,Zong, Ruifa,Thummel, Randolph P.,McFarland, Sherri A.

body text, p. 2889 - 2900 (2010/05/15)

Several mononuclear Ru(ll) dyads possessing 1, 10-phenanthrollne-appended pyrenylethynylene llgands were synthesized, characterized, and evaluated for their potential in photobiologlcal applications such as photodynamlc therapy (PDT). These complexes interact with DNA via intercalation and photocleave DNA in vitro at submlcromolar concentrations when irradiated with visible light (λirr ≥ 400 nm). Such properties are remarkably sensitive to the position of the ethynylpyrenyl substituent on the 1, 10-phenanthroline ring, with 3-substitutlon showing the strongest binding under all conditions and causing the most deleterious DNA damage. Both dyads photocleave DNA under hypoxic conditions, and this photoactlvity translates well to cytotoxicity and photocytotoxlcity models using human leukemia cells, where the 5- and 3-substituted dyads show photocytotoxiclty at 5-10μM and 10-20μM, respectively, with minimal, or essentially no, dark toxicity at these concentrations. This lack of dark cytotoxicity at concentrations where significant photoactlvity Is observed emphasizes that agents with strong intercalating units, previously thought to be too toxic for phototherapeutic applications, should not be excluded from the arsenal of potential photochemotherapeutic agents under investigation.

Liquid-crystalline phenanthrolines

Bousquet,Bruce

, p. 1769 - 1771 (2007/10/03)

The synthesis and mesomorphism of the first liquid-crystalline phenanthrolines are reported.

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