4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Base Information

Chemical Name:4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester
CAS No.:570397-03-4
Molecular Formula:C₃₂H₄₃N₃O₅S₂
Molecular Weight:613.843
Hs Code.:

4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-<i>o</i>-tolyl-3,6-dihydro-2<i>H</i>-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Synonyms:

Suppliers and Price of 4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

There total 13 articles about 4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10332-17-9,874219-77-9
Met-OMe

: 570397-03-4
4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / EDC; HOBT

2: 100 percent / HCl

With hydrogenchloride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1016/S0960-894X(03)00095-7

Reference yield:

: 16419-60-6
2-Methylphenylboronic acid

: 570397-03-4
4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 98 percent / Pd(dppf)Cl₂; CsF

2: NaBH₃CN

3: 77 percent / 1-chloroethylchloroformate

4: 84 percent / EDC; HOBT

5: 100 percent / HCl

With hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; carbonochloridic acid 1-chloro-ethyl ester; sodium cyanoborohydride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; cesium fluoride; 1: Suzuki coupling;
DOI:10.1016/S0960-894X(03)00095-7

Reference yield:

: 55279-30-6
methyl 3-aminoisonicotinate

: 570397-03-4
4-(1-methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-5-o-tolyl-3,6-dihydro-2H-pyridine-1-carboxylic acid 3-cyclohexyl-1-thiazol-5-yl-propyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 70 percent / NaNO₂; KI

2: 98 percent / Pd(dppf)Cl₂; CsF

3: NaBH₃CN

4: 77 percent / 1-chloroethylchloroformate

5: 84 percent / EDC; HOBT

6: 100 percent / HCl

With hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; carbonochloridic acid 1-chloro-ethyl ester; sodium cyanoborohydride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; cesium fluoride; potassium iodide; sodium nitrite; 2: Suzuki coupling;
DOI:10.1016/S0960-894X(03)00095-7