5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline

Base Information

• Chemical Name: 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline
• CAS No.: 835898-99-2
• Molecular Formula: C₂₃H₂₀N₂O₅S₂
• Molecular Weight: 468.554
• Mol file: 835898-99-2.mol

Synonyms:

Chemical Property of 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline

There total 5 articles about 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-hydroxy-8-p-tolylsulfonylaminoquinoline hydrochloride → 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline (835898-99-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (diacetoxy-λ³-iodanyl)benzene; sodium acetate / acetic acid

2: 1.2 g / 0.17 h

With [bis(acetoxy)iodo]benzene; sodium acetate; In acetic acid;

DOI:10.1007/s11178-005-0133-y

Reference yield:

8-nitroquinoline (607-35-2) → 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline (835898-99-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 55 percent / potassium hydroxide; hydroxylamine hydrochloride / ethanol / 1 h / 20 °C

2: 77 percent / potassium hydroxide / H₂O / Heating

3: 68 percent / tin(II) chloride; hydrochloric acid / 27 h

4: 89 percent / pyridine / methanol / 0.5 h

5: (diacetoxy-λ³-iodanyl)benzene; sodium acetate / acetic acid

6: 1.2 g / 0.17 h

With pyridine; hydrogenchloride; potassium hydroxide; [bis(acetoxy)iodo]benzene; hydroxylamine hydrochloride; sodium acetate; tin(ll) chloride; In methanol; ethanol; water; acetic acid;

DOI:10.1007/s11178-005-0133-y

Reference yield:

5-amino-8-nitroquinoline (42606-39-3) → 5-hydroxy-6-p-tolylsulfonyl-8-p-tolylsulfonylaminoquinoline (835898-99-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 77 percent / potassium hydroxide / H₂O / Heating

2: 68 percent / tin(II) chloride; hydrochloric acid / 27 h

3: 89 percent / pyridine / methanol / 0.5 h

4: (diacetoxy-λ³-iodanyl)benzene; sodium acetate / acetic acid

5: 1.2 g / 0.17 h

With pyridine; hydrogenchloride; potassium hydroxide; [bis(acetoxy)iodo]benzene; sodium acetate; tin(ll) chloride; In methanol; water; acetic acid;

DOI:10.1007/s11178-005-0133-y

upstream raw materials:

sodium 4-methylbenzenesulfinate

8-nitroquinoline

5-hydroxy-8-nitroquinoline

5-amino-8-nitroquinoline