5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione

Base Information

Chemical Name:5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione
CAS No.:308095-83-2
Molecular Formula:C₁₇H₁₁ClN₂O₄S
Molecular Weight:374.804
Hs Code.:
European Community (EC) Number:683-882-5
Wikidata:Q76324707

Synonyms:AKOS024424143;5-(4-CHLOROBENZYLIDENE)-3-(4-NITROBENZYL)-1,3-THIAZOLIDINE-2,4-DIONE

Suppliers and Price of 5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:374.0128057
Heavy Atom Count:25
Complexity:576

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C(=O)C(=CC3=CC=C(C=C3)Cl)SC2=O)[N+](=O)[O-]
Isomeric SMILES:C1=CC(=CC=C1CN2C(=O)/C(=C\C3=CC=C(C=C3)Cl)/SC2=O)[N+](=O)[O-]

Technology Process of 5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione

There total 2 articles about 5-(4-Chlorobenzylidene)-3-(4-nitrobenzyl)-1,3-thiazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

: 103753-40-8
3-(4-nitrobenzyl)-thiazolidine-2,4-dione

: 104-88-1
4-chlorobenzaldehyde

: 308095-83-2
5-(4-chlorobenzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione

Guidance literature:: With sodium acetate; In acetic acid; for 1.5h; Reflux;

Reference yield:

: 100-14-1
4-nitrobenzyl chloride

: 308095-83-2
5-(4-chlorobenzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 18 h / Reflux

2: sodium acetate / acetic acid / 1.5 h / Reflux

With sodium acetate; In acetic acid;