(Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate

Base Information

• Chemical Name: (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate
• CAS No.: 1316852-74-0
• Molecular Formula: C₂₅H₁₃N₅O₄S
• Molecular Weight: 479.475
• Mol file: 1316852-74-0.mol

Synonyms:

Chemical Property of (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate

There total 3 articles about (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

5-oxo-7-phenyl-2-thiol-3,5-dihydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitrile (1038081-88-7) + methyl 4-formylbenzoate (1571-08-0) → (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate (1316852-74-0)

Guidance literature:

With sodium acetate; acetic anhydride; acetic acid; chloroacetic acid; for 3h; Reflux;

Reference yield:

1-amino-6-(triphenylphosphoranylideneamino)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrileiminophosphorane (1038081-85-4) → (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate (1316852-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 3 h / 100 °C / Autoclave

2: sodium acetate; acetic anhydride; acetic acid; chloroacetic acid / 3 h / Reflux

With sodium acetate; acetic anhydride; acetic acid; chloroacetic acid; In toluene; 1: Aza-Wittig reaction;

Reference yield:

1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile (79388-04-8) → (Z)-methyl 4-((9-cyano-7-isocyano-3,6-dioxo-8-phenyl-3,6-dihydro-2H-thiazolo[3',2':2,3][1,2,4]triazolo[1,5-a]pyridin-2-ylidene)methyl)benzoate (1316852-74-0)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / hexachloroethane; toluene / 2 h / Reflux

2: toluene / 3 h / 100 °C / Autoclave

3: sodium acetate; acetic anhydride; acetic acid; chloroacetic acid / 3 h / Reflux

With sodium acetate; acetic anhydride; acetic acid; triethylamine; chloroacetic acid; In hexachloroethane; toluene; 1: Kirsanov reaction / 2: Aza-Wittig reaction;

upstream raw materials:

5-oxo-7-phenyl-2-thiol-3,5-dihydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitrile

methyl 4-formylbenzoate

1-amino-6-(triphenylphosphoranylideneamino)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrileiminophosphorane

1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile