3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester

Base Information

Chemical Name:3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester
CAS No.:1233353-87-1
Molecular Formula:C₂₅H₂₄FNO₅S
Molecular Weight:469.534
Hs Code.:
Mol file:1233353-87-1.mol

Synonyms:

Suppliers and Price of 3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-FluorobenzenesulfonicAcid5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizin-9-ylEster
25mg
$ 1540.00

TRC
3-FluorobenzenesulfonicAcid5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizin-9-ylEster
2.5mg
$ 195.00

Total 3 raw suppliers

Chemical Property of 3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

3-FluorobenzenesulfonicAcid5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizin-9-ylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester is a derivative of Corydaline, a pharmacologically active isoquinoline alkaloid isolated from Corydalistubers and is known to exhibit antiacetylcholinesterase, antiallergic, antinociceptive and gastric emptying activities.

Technology Process of 3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester

There total 7 articles about 3-Fluorobenzenesulfonic Acid 5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizin-9-yl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.2%

: 1233354-62-5
2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate

: 1233353-87-1,1233354-49-8,1233354-53-4
3,10-dimethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[2,1-b]isoquinolin-9-yl 3-fluorobenzenesulfonate

Guidance literature:: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate; With trichlorophosphate; In toluene; for 2h; Reflux;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h; Cooling with ice;

Reference yield:

: 1233354-60-3
7-methoxy-3-oxo-3,4-dihydro-1H-2-benzopyran-8-yl 3-fluorobenzene-1-sulfonate

: 1233353-87-1,1233354-49-8,1233354-53-4
3,10-dimethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[2,1-b]isoquinolin-9-yl 3-fluorobenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / methanol / 8 h / Reflux

2.1: trichlorophosphate / toluene / 2 h / Reflux

2.2: 0.5 h / 20 °C / Cooling with ice

With triethylamine; trichlorophosphate; In methanol; toluene;

Reference yield:

: 56201-87-7
8-hydroxy-7-methoxyisobenzofuranyltetrahydropyran-3-one

: 1233353-87-1,1233354-49-8,1233354-53-4
3,10-dimethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[2,1-b]isoquinolin-9-yl 3-fluorobenzenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 4 h / 20 °C

2.1: triethylamine / methanol / 8 h / Reflux

3.1: trichlorophosphate / toluene / 2 h / Reflux

3.2: 0.5 h / 20 °C / Cooling with ice

With triethylamine; trichlorophosphate; In methanol; dichloromethane; toluene;