1233354-62-5

Basic information

• Product Name: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate
• Synonyms: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate
• CAS NO: 1233354-62-5
• Molecular Weight: 503.548
• Mol File: 1233354-62-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate(1233354-62-5)
• EPA Substance Registry System: 2-(hydroxymethyl)-6-methoxy-3-({[2-(3-methoxyphenyl)ethyl]carbamoyl}methyl)phenyl-3-fluorobenzene-1-sulfonate(1233354-62-5)

Safety Data

• Hazardous Substances Data: 1233354-62-5(Hazardous Substances Data)

Upstream product

• 104-01-8 4-Methoxyphenylacetic acid 
• 774-81-2 (3-bromo-4-methoxy-phenyl)-acetic acid 
• 1131-94-8 homoisovanillic acid 
• 56201-87-7 8-hydroxy-7-methoxyisobenzofuranyltetrahydropyran-3-one 
• 1233354-60-3 7-methoxy-3-oxo-3,4-dihydro-1H-2-benzopyran-8-yl 3-fluorobenzene-1-sulfonate 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 1233353-87-1 3,10-dimethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[2,1-b]isoquinolin-9-yl 3-fluorobenzenesulfonate 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING NASH, NAFLD, AND OBESITY

The present technology relates to methods of treating NASH, NAFLD and/or obesity using compounds of Formulas I, II, III, IV, V, and/or VI. The methods include administering to a subject suffering from one or more of non-alcoholic steatohepatitis (NASH), non- alcoholic fatty liver disease (NAFLD) and/or obesity a therapeutically effective amount of such a compound

Tetrahydroberberine derivative and application thereof

The invention relates to a tetrahydroberberine derivative and application thereof and relates to a compound represented by a formula (V) shown in the description, a preparation method therefor and application of the compound in medicine. Particularly, the invention relates to a derivative of the compound represented by the general formula (V), a preparation method for the derivative of the compound and use of the derivative of the compound in the prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, fatty degeneration of liver, type II diabetes, hyperglycemia, obesity or insulin resistance syndrome and metabolic syndrome. The compound disclosed by the invention can also be used for lowering total cholesterol, LDL (Low-Density Lipoprotein)-cholesterol and triglyceride, improving liver LDL receptor expression and inhibiting PCSK9 expression.

Compounds and Compositions for Modulating Lipid Levels and Methods of Preparing Same

The present technology relates to compounds of Formulas I-VI and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also increase HDL-C, lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated protein kinase.