Technology Process of 2,3,7-trideoxy-6-O-trityl-L-erythro-2-hepteno-4-pyranosulose
There total 6 articles about 2,3,7-trideoxy-6-O-trityl-L-erythro-2-hepteno-4-pyranosulose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
tetrahydrofuran; water;
for 15h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 70 percent / DMAP / dimethylformamide / 72 h / 70 °C
2: 63 percent / LiAlH4 / diethyl ether / 0.67 h / Ambient temperature
3: 85 percent / oxalyl chloride, DMSO, Et3N / CH2Cl2 / 0.33 h / -60 °C
5: 93 percent / Na2CO3, Br2 / methanol / 1.) 15 min, -56 deg C, 2.) 45 min, RT
6: 94 percent / p-MeC6H4SO3H*H2O / tetrahydrofuran; H2O / 15 h / Ambient temperature
With
dmap; lithium aluminium tetrahydride; oxalyl dichloride; bromine; sodium carbonate; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 63 percent / LiAlH4 / diethyl ether / 0.67 h / Ambient temperature
2: 85 percent / oxalyl chloride, DMSO, Et3N / CH2Cl2 / 0.33 h / -60 °C
4: 93 percent / Na2CO3, Br2 / methanol / 1.) 15 min, -56 deg C, 2.) 45 min, RT
5: 94 percent / p-MeC6H4SO3H*H2O / tetrahydrofuran; H2O / 15 h / Ambient temperature
With
lithium aluminium tetrahydride; oxalyl dichloride; bromine; sodium carbonate; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
