123077-62-3

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 76-83-5 trityl chloride 
• 687-47-8 (S)-Ethyl lactate 
• 5333-62-0 benzyl trityl ether 

Downstream Products

• 123077-64-5 (S)-2-trityloxypropanal 
• 850308-46-2 (2E,4S)-4-trityloxypent-2-en-1-ol 
• 850308-44-0 ethyl (2E,4S)-4-(trityloxy)pent-2-enoate 
• 1026001-58-0 2,2,2-Trichloro-acetimidic acid (E)-(S)-4-trityloxy-pent-2-enyl ester 
• 161554-88-7 (E)-(S)-4-Trityloxy-pent-2-enoic acid tert-butyl ester 
• 194367-52-7 (3S,4S)-3-Benzylamino-4-trityloxy-pentanoic acid tert-butyl ester 
• 1026372-78-0 (2S,3S,4S)-3-Benzylamino-2-((R)-1-hydroxy-ethyl)-4-trityloxy-pentanoic acid tert-butyl ester 
• 161554-76-3 (3S,4S)-1-Benzyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-((S)-1-trityloxy-ethyl)-azetidin-2-one 
• 161554-75-2 (2S,3S,4S)-3-Benzylamino-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-trityloxy-pentanoic acid tert-butyl ester 
• 1312778-64-5 dimethyl (S)-2-oxo-3-(trityloxy)butylphosphonate 
• 1312778-67-8 allyl (E,5S)-4-hydroxy-5-(trityloxy)hex-2-enoate 
• 1312778-66-7 allyl (E,5S)-4-hydroxy-5-(trityloxy)hex-2-enoate 
• 1312778-65-6 allyl (S,E)-4-oxo-5-(trityloxy)hex-2-enoate 
• 1312778-71-4 C₃₈H₄₄O₉ 

Relevant academic research and scientific papers

Enantioselective total synthesis of macrosphelides A and e

Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lactic acid is described. Key features of the synthesis include the utility of a hitherto unexplored β-ketophosphonate derived from lactic acid and Yamaguchi lactonization leading to the title compounds.

Friedel-Crafts catalysts as assistants in the tritylation of less reactive hydroxyls

Less reactive hydroxyls, such as those present in secondary alcohols and in some primary alcohols, phenols and carboxylic acids, were easily tritylated with the homogeneous assistance of equimolar quantities of chlorides of di- and trivalent metals in apr

A highly stereoselective ether directed palladium catalysed aza-Claisen rearrangement

A highly stereoselective rearrangement of allylic trichloroacetimidates to allylic trichloroamides has been achieved using adjacent ether groups to direct facial coordination of the palladium(II) catalyst. The Royal Society of Chemistry 2005.

Benzyl trityl ether and DDQ as new tritylating reagents

We describe herein a new tritylation procedure of alcohols using benzyl trityl ether and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone. The reaction involves oxidative abstraction of one of the benzylic protons of benzyl trityl ether, followed by transformation of the generated benzyl trityl ether cation into a complex of benzaldehyde and trityl cation. The present procedure proceeds under mild neutral conditions to afford trityl ethers in generally good yields for primary alcohols, and in acceptable yields for several secondary alcohols.

Highly Diastereoselective Conjugate Addition of Lithium Dialkylamides to α,β-Unsaturated Esters Having a Chiral Center at the γ-Position

The conjugate addition of lithium amides 2 to tert-butyl 4-(OR)-substituted-2-pentenoates 1 produced a mixture of the syn- and anrt-amino esters (3 and 4) in high yields. Sterically bulky OR groups, such as trityloxy and tert-butyldiphenylsilyloxy, gave t

Convenient method for the preparation of trityl ethers from secondary alcohols

The preparation of trityl ethers from secondary alcohols (10 mmol) with triphenylmethyl chloride (1.2 eq.) is carried out at room temperature by using DBU (1.4 eq.) as base in CH2Cl2. The high yielding procedure is very simple and it

Synthesis of (-)-Biopterin

The synthesis of (-)-biopterin (1) was accomplished by employing (1S,2S)-1-(2-furyl)-2-(trityloxy)-1-propanol (6), derived from ethyl (S)-lactate, as building block for the side chain.