S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide

Base Information

• Chemical Name: S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide
• CAS No.: 145231-33-0
• Molecular Formula: BrH*C₁₆H₂₂N₄S
• Molecular Weight: 383.355
• Mol file: 145231-33-0.mol

Synonyms:

Chemical Property of S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide

There total 3 articles about S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

N-(3-Phenylpropyl)thiourea (93168-20-8) + 4-(3-bromopropyl)-1H-imidazole hydrobromide (52237-36-2) → S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide (145231-33-0)

Guidance literature:

In ethanol; for 72h;

DOI:10.1016/0223-5234(92)90185-4

Reference yield:

3-Phenylpropan-1-amine (2038-57-5) → S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide (145231-33-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / CH₂Cl₂ / 2 h

2: 72 percent / aq. K₂CO₃ / ethanol / 2 h / Heating

3: 20 percent / ethanol / 72 h

With potassium carbonate; In ethanol; dichloromethane;

DOI:10.1016/0223-5234(92)90185-4

Reference yield:

N-((3-phenylpropyl)carbamothioyl)benzamide (145383-01-3) → S-<3-(4(5)-imidazolyl)propyl>-N-(3-phenylpropyl)isothiourea dihydrobromide (145231-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / aq. K₂CO₃ / ethanol / 2 h / Heating

2: 20 percent / ethanol / 72 h

With potassium carbonate; In ethanol;

DOI:10.1016/0223-5234(92)90185-4

upstream raw materials:

N-(3-Phenylpropyl)thiourea

4-(3-bromopropyl)-1H-imidazole hydrobromide

3-Phenylpropan-1-amine

N-((3-phenylpropyl)carbamothioyl)benzamide

Refernces