Technology Process of 1-methyl-6-demethyl-6-propyl-9,10-dihydroergocristine
There total 4 articles about 1-methyl-6-demethyl-6-propyl-9,10-dihydroergocristine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonia; ferric nitrate;
In
diethyl ether;
for 2h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 69 percent / H2 / Raney Ni / dioxane; H2O / 4 h / 40 °C / 760 Torr
2: 55 percent / sodium cyanoborohydride, acetic acid / methanol; CHCl3 / 4 h / Ambient temperature; pH 5.2
3: 49 percent / K, liquid ammonia, iron(III) nitrate / diethyl ether / 2 h
With
ammonia; hydrogen; sodium cyanoborohydride; acetic acid; ferric nitrate;
nickel;
In
1,4-dioxane; methanol; diethyl ether; chloroform; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / CHCl3 / 30 h / Ambient temperature
2: 69 percent / H2 / Raney Ni / dioxane; H2O / 4 h / 40 °C / 760 Torr
3: 55 percent / sodium cyanoborohydride, acetic acid / methanol; CHCl3 / 4 h / Ambient temperature; pH 5.2
4: 49 percent / K, liquid ammonia, iron(III) nitrate / diethyl ether / 2 h
With
ammonia; hydrogen; sodium cyanoborohydride; acetic acid; ferric nitrate;
nickel;
In
1,4-dioxane; methanol; diethyl ether; chloroform; water;
