benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate

Base Information

• Chemical Name: benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate
• CAS No.: 96326-24-8
• Molecular Formula: C₂₈H₃₅NO₇
• Molecular Weight: 497.588
• Mol file: 96326-24-8.mol

Synonyms:

Chemical Property of benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate

There total 4 articles about benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.7%

benzyl (E)-2-butenoate (71338-71-1) + C17H23NO5 (96326-21-5) → benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate (96326-23-7,96326-24-8,96347-28-3) + benzyl (-)-(3,4-cis,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate (96347-28-3)

Guidance literature:

In benzene; for 16h; Heating;

DOI:10.1021/jo00213a025

Reference yield:

ethyl 3,3-(ethylenedioxy)-4-formylbutyrate (32296-85-8) → benzyl (-)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1S)-1-phenylethyl)isoxazolidine-4-carboxylate (96326-23-7,96326-24-8,96347-28-3)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 1 h / 50 °C

2: 27.4 percent / benzene / 16 h / Heating

In benzene;

DOI:10.1021/jo00213a025

Reference yield:

ethyl 3,3-(ethylenedioxy)-4-formylbutyrate (32296-85-8) → benzyl (+)-(3,4-trans,4,5-trans)-3-<3-(ethoxycarbonyl)-2,2-(ethylenedioxy)propyl>-5-methyl-2-((1R)-1-phenylethyl)isoxazolidine-4-carboxylate (96326-23-7,96326-24-8,96347-28-3)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 1 h / 50 °C

2: benzene / 16 h / Heating

In benzene;

DOI:10.1021/jo00213a025

upstream raw materials:

benzyl (E)-2-butenoate

C₁₇H₂₃NO₅

ethyl 3,3-(ethylenedioxy)-4-formylbutyrate

C₁₇H₂₃NO₅