{(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium⁽⁰⁾

Base Information

• Chemical Name: {(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium⁽⁰⁾
• CAS No.: 121809-09-4
• Molecular Formula: C₁₅H₁₁CrNO₇
• Molecular Weight: 369.251
• Mol file: 121809-09-4.mol

Synonyms:

Chemical Property of {(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium⁽⁰⁾

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium⁽⁰⁾

There total 1 articles about {(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium⁽⁰⁾ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

pentacarbonyl((methyl)((tetramethylammonio)oxy)carbene)chromium(0) (15975-93-6) + Acetyl bromide (506-96-7) + O-benzyl carbamate (621-84-1) → {(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium(0) (121809-09-4) + (aminobenzylidene)pentacarbonylchromium(0) (32370-44-8)

Guidance literature:

In methanol; dichloromethane; in a airlessware flask, under Ar, addn. of AcBr to the soln. of (CH3)4NO(CH3)CCr(CO)5 at - 40 ° C, stirring 1 h, addn. of a soln. of O-benzyl carbamate, stirring 6 h at -40 °C, warming to -15 °C, 22 h at this temp.; filtration (through Celite), chromy.(silica gel column, eluent a) hexane, then 7:1 hexane/Et-acetate), evapn., elem. anal.;

DOI:10.1021/om00111a015

Reference yield: 67.0%

{(N-carbobenzoxyamino)methylcarbene}pentacarbonylchromium(0) (121809-09-4) → methyl N-benzyloxycarbonylalaninate (64562-95-4)

Guidance literature:

In methanol; Irradiation (UV/VIS); in a Schlenk tube, under Ar, bubbling Ar through the deep red soln., 5 min, irradn. ( 450-W mercury lamp) 15.5 h, solvent evapn., dissolving the residue in 1:1 hexane/Et acetate, air oxidn. in a light box; filtration (through Celite), evapn. (rotatory), radial chromy. (silica gel, 10% hexane/Et acetate, elem. anal.;

DOI:10.1021/om00111a015

upstream raw materials:

pentacarbonyl((methyl)((tetramethylammonio)oxy)carbene)chromium⁽⁰⁾

Acetyl bromide

O-benzyl carbamate

Downstream raw materials:

methyl N-benzyloxycarbonylalaninate