Ethyl [(3,4-difluorophenyl)amino](oxo)acetate

Base Information

Chemical Name:Ethyl [(3,4-difluorophenyl)amino](oxo)acetate
CAS No.:333441-81-9
Molecular Formula:C₁₀H₉F₂NO₃
Molecular Weight:229.183
Hs Code.:
DSSTox Substance ID:DTXSID201236826

Synonyms:ethyl [(3,4-difluorophenyl)amino](oxo)acetate;333441-81-9;ethyl 2-(3,4-difluoroanilino)-2-oxoacetate;ethyl [(3,4-difluorophenyl)carbamoyl]formate;DTXSID201236826;STK082623;AKOS003280364;BS-4346;ethyl[(3,4-difluorophenyl)carbamoyl]formate;EN300-236282;Ethyl 2-[(3,4-difluorophenyl)amino]-2-oxoacetate

Suppliers and Price of Ethyl [(3,4-difluorophenyl)amino](oxo)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl [(3,4-difluorophenyl)amino](oxo)acetate

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:229.05504947
Heavy Atom Count:16
Complexity:273

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(=O)NC1=CC(=C(C=C1)F)F

Technology Process of Ethyl [(3,4-difluorophenyl)amino](oxo)acetate

There total 1 articles about Ethyl [(3,4-difluorophenyl)amino](oxo)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4755-77-5
Ethyl oxalyl chloride

: 3863-11-4
3,4-difluoroaniline

: 333441-81-9
C₁₀H₉F₂NO₃

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1021/jm3002247

Reference yield:

: 333441-81-9
C₁₀H₉F₂NO₃

: N¹-(3,4-difluorophenyl)-N²-((5-(2-hydroxyethyl)-4-methylthiazol-2-yl)(piperidin-2-yl)methyl)oxalamide dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / ethanol

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine

With water; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; sodium hydroxide; In ethanol;
DOI:10.1021/jm3002247

Reference yield:

: 333441-81-9
C₁₀H₉F₂NO₃

: 1376434-51-3
C₁₉H₂₂F₂N₄O₃S

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / ethanol

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine

With water; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; sodium hydroxide; In ethanol;
DOI:10.1021/jm3002247