methyl 2-(5-methyl-2-nitrophenoxy)acetate

Base Information

• Chemical Name: methyl 2-(5-methyl-2-nitrophenoxy)acetate
• CAS No.: 138035-73-1
• Molecular Formula: C10H11NO5
• Molecular Weight: 225.19800
• Mol file: 138035-73-1.mol

Synonyms:(5-Methyl-2-nitro-phenoxy)-acetic acid methyl ester;(5-Methyl-2-nitro-phenoxy)-essigsaeure-methylester;

Chemical Property of methyl 2-(5-methyl-2-nitrophenoxy)acetate

Chemical Property:

• PSA: 81.35000
• LogP: 1.97820

Purity/Quality:

99% ^*data from raw suppliers

Methyl2-(5-methyl-2-nitrophenoxy)acetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(5-methyl-2-nitrophenoxy)acetate

There total 4 articles about methyl 2-(5-methyl-2-nitrophenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-5-methylphenol (700-38-9) + bromoacetic acid methyl ester (96-32-2) → (5-methyl-2-nitro-phenoxy)-acetic acid methyl ester (138035-73-1)

Guidance literature:

With potassium carbonate; In acetonitrile;

DOI:10.1007/s00044-022-02847-5

Reference yield:

2-nitro-5-methylphenol (700-38-9) → (5-methyl-2-nitro-phenoxy)-acetic acid methyl ester (138035-73-1)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOH-solution

2: thionyl chloride

With sodium hydroxide; thionyl chloride;

Reference yield:

(5-methyl-2-nitro-phenoxy)-acetic acid (869944-70-7) → (5-methyl-2-nitro-phenoxy)-acetic acid methyl ester (138035-73-1)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

With thionyl chloride;

upstream raw materials:

methanol

2-nitro-5-methylphenol

(5-methyl-2-nitro-phenoxy)-acetic acid

bromoacetic acid methyl ester