3-Chloro-2-phenoxyaniline

Base Information

• Chemical Name: 3-Chloro-2-phenoxyaniline
• CAS No.: 3169-75-3
• Molecular Formula: C₁₂H₁₀ClNO
• Molecular Weight: 219.671
• European Community (EC) Number: 872-759-3
• Mol file: 3169-75-3.mol

Synonyms:3-CHLORO-2-PHENOXYANILINE;3169-75-3;SCHEMBL3794304;AKOS000215499;SB79520;CS-0245564;EN300-306796;G53213

Chemical Property of 3-Chloro-2-phenoxyaniline

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 219.0450916
• Heavy Atom Count: 15
• Complexity: 194

Purity/Quality:

98%min ^*data from raw suppliers

3-chloro-2-phenoxyaniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=C(C=CC=C2Cl)N

Technology Process of 3-Chloro-2-phenoxyaniline

There total 3 articles about 3-Chloro-2-phenoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Nitro-6-chlor-1-phenoxy-benzol (3169-74-2) → 3-chloro-2-phenoxyaniline (3169-75-3)

Guidance literature:

With hydrogen; nickel; In ethyl acetate;

DOI:10.1002/hlca.19650480212

Reference yield:

1,2-Dichloro-3-nitrobenzene (3209-22-1) → 3-chloro-2-phenoxyaniline (3169-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH

2: H₂ / Raney-Ni / ethyl acetate

With potassium hydroxide; hydrogen; nickel; In ethyl acetate;

DOI:10.1002/hlca.19650480212

Reference yield:

phenol (108-95-2,27073-41-2) → 3-chloro-2-phenoxyaniline (3169-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH

2: H₂ / Raney-Ni / ethyl acetate

With potassium hydroxide; hydrogen; nickel; In ethyl acetate;

DOI:10.1002/hlca.19650480212

upstream raw materials:

2-Nitro-6-chlor-1-phenoxy-benzol

1,2-Dichloro-3-nitrobenzene

phenol

Downstream raw materials:

(3-Chloro-2-phenoxy-phenyl)-imidazolidin-2-ylidene-amine

(3-Chloro-2-phenoxy-phenyl)-thiourea

1-Benzoyl-3-(3-chloro-2-phenoxy-phenyl)-thiourea

3-Chlor-2-phenoxitrifluormethansulfonanilid