C₂₀H₃₂NO₆PSi

Base Information

• Chemical Name: C₂₀H₃₂NO₆PSi
• CAS No.: 1026613-99-9
• Molecular Formula: C₂₀H₃₂NO₆PSi
• Molecular Weight: 441.536
• Mol file: 1026613-99-9.mol

Synonyms:

Chemical Property of C₂₀H₃₂NO₆PSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₃₂NO₆PSi

There total 7 articles about C₂₀H₃₂NO₆PSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-2-benzyloxycarbonylamino-4-bromo-butyric acid methyl ester (15159-67-8) → C20H32NO6PSi (1026613-99-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 98 percent / NaBH₄ / ethanol / 20 °C

2.1: 83 percent / H₂O₂; pyridine / CH₂Cl₂ / 2 h / Heating

3.1: 85 percent / NH₄H₂PO₂; Et₃B; O₂ / methanol; hexane / 2 h / 20 °C

4.1: CH₂Cl₂ / 4 h / Heating

5.1: CH₂Cl₂ / 22 h / Heating

5.2: N,O-bis(trimethylsilyl)acetamide / CH₂Cl₂ / 18 h / Heating

With pyridine; sodium tetrahydroborate; ammonium hypophosphorous acid; triethyl borane; dihydrogen peroxide; oxygen; In methanol; ethanol; hexane; dichloromethane; 5.1: Arbuzov reaction;

DOI:10.1021/jo0507439

Reference yield:

N-benzyloxycarbonyl-L-α-vinylglycine methyl ester (75266-40-9) → C20H32NO6PSi (1026613-99-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 85 percent / NH₄H₂PO₂; Et₃B; O₂ / methanol; hexane / 2 h / 20 °C

2.1: CH₂Cl₂ / 4 h / Heating

3.1: CH₂Cl₂ / 22 h / Heating

3.2: N,O-bis(trimethylsilyl)acetamide / CH₂Cl₂ / 18 h / Heating

With ammonium hypophosphorous acid; triethyl borane; oxygen; In methanol; hexane; dichloromethane; 3.1: Arbuzov reaction;

DOI:10.1021/jo0507439

Reference yield:

methyl (S)-2-<<(benzyloxy)carbonyl>amino>-4-(methylsulfinyl)butanoate (75266-39-6) → C20H32NO6PSi (1026613-99-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 62 percent / 1,3,5-trimethyl-benzene / 24 h / Heating

2.1: 85 percent / NH₄H₂PO₂; Et₃B; O₂ / methanol; hexane / 2 h / 20 °C

3.1: CH₂Cl₂ / 4 h / Heating

4.1: CH₂Cl₂ / 22 h / Heating

4.2: N,O-bis(trimethylsilyl)acetamide / CH₂Cl₂ / 18 h / Heating

With ammonium hypophosphorous acid; triethyl borane; oxygen; In methanol; hexane; dichloromethane; 1,3,5-trimethyl-benzene; 4.1: Arbuzov reaction;

DOI:10.1021/jo0507439

upstream raw materials:

1-bromo-4-butene

(S)-2-benzyloxycarbonylamino-4-hydroxyphosphinoyl-butyric acid methyl ester

(2S)-2-benzyloxycarbonylamino-4-bromo-butyric acid methyl ester

N-benzyloxycarbonyl-L-α-vinylglycine methyl ester