15159-67-8

Basic information

• Product Name: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2S)-
• Synonyms: L-Methyl-benzyloxycarbonyl-L-α-amino-γ-brombutyrat;(L)-methyl 2-benzyloxycarbonylamino-4-bromobutanoate;4-Brom-2-carbobenzyloxyamino-buttersaeuremethylester;(S)-2-benzyloxycarbonylamino-4-bromobutyric acid methyl ester;benzyl (S)-1-(methoxycarbonyl)-3-bromopropylcarbamate;(S)-2-benzyloxycarbonylamino-4-bromo-butyric acid methyl ester
• CAS NO: 15159-67-8
• Molecular Formula: C13H16BrNO4
• Molecular Weight: 330.178
• Mol File: 15159-67-8.mol
• Article Data: 19

Chemical Properties

• Melting Point: 61 °C
• Boiling Point: 444.5±45.0 °C(Predicted)
• Density: 1.410±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2S)-(15159-67-8)
• EPA Substance Registry System: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2S)-(15159-67-8)

Safety Data

• Hazardous Substances Data: 15159-67-8(Hazardous Substances Data)

Upstream product

• 15159-66-7 α-amino-γ-bromobutyric acid methyl ester hydrochloride 
• 501-53-1 benzyl chloroformate 
• 67-56-1 methanol 
• 15159-65-6 (2S)-2-amino-4-bromobutanoic acid hydrobromide 
• 4668-37-5 N-(benzyloxycarbonyl)asparagine methyl ester 
• 2185-03-7 L-homoserine lactone hydrochloride 
• 58578-43-1 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid dicyclohexylamine salt 
• 35677-88-4 N-benzyloxycarbonyl-(L)-homoserine 
• 101650-17-3 (S)-2-amino-4-bromobutyric acid methyl ester 
• 314728-04-6 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester 
• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 4668-42-2 (S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester 
• 5672-83-3 Z-L-GluOMe 

Downstream Products

• 15159-68-9 N^α'-Benzyloxycarbonyl-L-cystathionin-α'-methylester; (L-2-Amino-7-benzyloxycarbonylamino-4-thiaoctan-1-saeure-8-saeuremethylester 
• 1187361-37-0 benzyl (S)-1-(methoxycarbonyl)-3-(4-methoxyphenylthio)propylcarbamate 
• 1187361-20-1 benzyl (S)-1-(methoxycarbonyl)-3-(propylthio)propylcarbamate 
• 1187361-22-3 benzyl (S)-1-(methoxycarbonyl)-3-(butylthio)propylcarbamate 
• 1187361-24-5 benzyl (S)-1-(methoxycarbonyl)-3-(hexylthio)propylcarbamate 
• 1187361-26-7 benzyl (S)-1-(methoxycarbonyl)-3-(octylthio)propylcarbamate 
• 1187361-52-9 benzyl (S)-1-(methoxycarbonyl)-3-(decylthio)propylcarbamate 
• 1187361-39-2 benzyl (S)-1-(methoxycarbonyl)-3-(2-nitrophenylthio)propylcarbamate 
• 1187361-35-8 benzyl (S)-1-(methoxycarbonyl)-3-(phenylthio)propylcarbamate 
• 1187361-21-2 benzyl (S)-1-(methoxycarbonyl)-3-(isopropylthio)propylcarbamate 
• 1229597-26-5 benzyl (S)-1-(methoxycarbonyl)-3-(benzylthio)propylcarbamate 
• 1187361-36-9 benzyl (S)-1-(methoxycarbonyl)-3-(4-chlorophenylthio)propylcarbamate 
• 1187361-38-1 benzyl (S)-1-(methoxycarbonyl)-3-(4-nitrophenylthio)propylcarbamate 
• 120286-25-1 (2S)-2-{[(benzyloxy)carbonyl]amino}-4-(diethoxyphosphoryl)butanoic acid 

Relevant articles and documents

A Simple Synthesis of 1-Aminocyclopropane-1-carboxylic Acid

Conversion of N-carbobenzyloxy-L-glutamic acid α-methylester (Z-L-glu(OH)OCH3, 1) into the bromo derivative 2 and subsequent γ-elimination by the use of sodium hydride leads to the fully protected synthon 3 in good yields.Deprotection by sodium hydroxide and hydrogenolysis yields almost quantitively the key substance 5.

HERBICIDAL COMPOSITIONS

The present invention relates novel herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations of the invention comprise at least one pyridazine derivative as defined herein, in combination with at least one futher herbicide that is an acetoclactase synthase (ALS) inhibitor.

HERBICIDAL COMPOSITIONS

The present invention relates to herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations comprising at least one pyridazine derivative of Formula (I) as defined herein, in combination with at least one further herbicide that is a compound of Formula (II) as defined herein.