N-[4-(chloroacetyl)benzyl]acetamide

Base Information

Chemical Name:N-[4-(chloroacetyl)benzyl]acetamide
CAS No.:24095-56-5
Molecular Formula:C₁₁H₁₂ClNO₂
Molecular Weight:225.675
Hs Code.:2925190090
European Community (EC) Number:838-413-0
DSSTox Substance ID:DTXSID70368881
Wikidata:Q82155754
ChEMBL ID:CHEMBL1517411
Mol file:24095-56-5.mol

Synonyms:24095-56-5;N-[4-(chloroacetyl)benzyl]acetamide;N-(4-(2-Chloroacetyl)benzyl)acetamide;N-[[4-(2-chloroacetyl)phenyl]methyl]acetamide;N-{[4-(2-chloroacetyl)phenyl]methyl}acetamide;HMS2695J12;MLS001007366;CHEMBL1517411;DTXSID70368881;AKOS008987369;SMR000384599;CS-0308513;EN300-12303;SR-01000064756;SR-01000064756-1;Z85921206

Suppliers and Price of N-[4-(chloroacetyl)benzyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-{[4-(2-chloroacetyl)phenyl]methyl}acetamide
250mg
$ 310.00

Crysdot
N-(4-(2-Chloroacetyl)benzyl)acetamide 95+%
1g
$ 589.00

American Custom Chemicals Corporation
N-[4-(CHLOROACETYL)BENZYL]ACETAMIDE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
N-[4-(CHLOROACETYL)BENZYL]ACETAMIDE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
N-[4-(CHLOROACETYL)BENZYL]ACETAMIDE 95.00%
1G
$ 852.55

Alichem
N-(4-(2-Chloroacetyl)benzyl)acetamide
1g
$ 513.60

AK Scientific
N-[4-(Chloroacetyl)benzyl]acetamide
2.5g
$ 1065.00

Total 8 raw suppliers

Chemical Property of N-[4-(chloroacetyl)benzyl]acetamide

Chemical Property:

Vapor Pressure:9.57E-09mmHg at 25°C
Boiling Point:462.8°Cat760mmHg
Flash Point:233.7°C
PSA：49.66000
Density:1.202g/cm³
LogP:2.58450
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:225.0556563
Heavy Atom Count:15
Complexity:235

Purity/Quality:

97% ^*data from raw suppliers

N-{[4-(2-chloroacetyl)phenyl]methyl}acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NCC1=CC=C(C=C1)C(=O)CCl

Technology Process of N-[4-(chloroacetyl)benzyl]acetamide

There total 3 articles about N-[4-(chloroacetyl)benzyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 588-46-5
N-(phenylmethyl)acetamide

: 79-04-9
chloroacetyl chloride

: 24095-56-5
4-Acetaminomethyl-ω-chlor-acetophenon

Guidance literature:: With aluminium trichloride; In 1,2-dichloro-ethane; at 20 ℃;
DOI:10.1016/S0960-894X(00)00128-1

Reference yield:

: 100-46-9
benzylamine

: 24095-56-5
4-Acetaminomethyl-ω-chlor-acetophenon

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / CH₂Cl₂ / 20 °C

2: AlCl₃ / 1,2-dichloro-ethane / 20 °C

With sodium hydroxide; aluminium trichloride; In dichloromethane; 1,2-dichloro-ethane; 1: Acetylation / 2: Friedel-Crafts reaction;
DOI:10.1016/S0960-894X(00)00128-1